Cargando…

Insights into White Matter Defect in Huntington’s Disease

Huntington’s disease (HD) is an autosomal-dominant inherited progressive neurodegenerative disorder. It is caused by a CAG repeat expansion in the Huntingtin gene that is translated to an expanded polyglutamine (PolyQ) repeat in huntingtin protein. HD is characterized by mood swings, involuntary mov...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Yize, Tong, Huichun, Yang, Tianqi, Liu, Li, Li, Xiao-Jiang, Li, Shihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656068/ https://www.ncbi.nlm.nih.gov/pubmed/36359783 http://dx.doi.org/10.3390/cells11213381

Ejemplares similares

Huntingtin Interacting Proteins and Pathological Implications
por: Liu, Li, et al.
Publicado: (2023)

Multiple pathways contribute to the pathogenesis of Huntington disease
por: Li, Shihua, et al.
Publicado: (2006)

Deep White Matter in Huntington's Disease
por: Phillips, Owen, et al.
Publicado: (2014)

Characterizing White Matter in Huntington's Disease
por: Gregory, Sarah, et al.
Publicado: (2019)

Transgenic animal models for study of the pathogenesis of Huntington’s disease and therapy
por: Chang, Renbao, et al.
Publicado: (2015)

Neuropsychiatry and White Matter Microstructure in Huntington’s Disease
por: Gregory, Sarah, et al.
Publicado: (2015)

Major Superficial White Matter Abnormalities in Huntington's Disease
por: Phillips, Owen R., et al.
Publicado: (2016)

Use of large animal models to investigate Huntington's diseases
por: Yan, Sen, et al.
Publicado: (2019)

Linking white matter and deep gray matter alterations in premanifest Huntington disease
por: Faria, Andreia V., et al.
Publicado: (2016)

White matter predicts functional connectivity in premanifest Huntington's disease
por: McColgan, Peter, et al.
Publicado: (2017)

In vivo characterization of white matter pathology in premanifest huntington's disease
por: Zhang, Jiaying, et al.
Publicado: (2018)

A Critical Review of White Matter Changes in Huntington’s Disease
por: Casella, Chiara, et al.
Publicado: (2020)

Developmental Whole Brain White Matter Alterations in Transgenic Huntington’s Disease Monkey
por: Meng, Yuguang, et al.
Publicado: (2017)

Neuroinflammation in Huntington’s disease: From animal models to clinical therapeutics
por: Jia, Qingqing, et al.
Publicado: (2022)

Natural biological variation of white matter microstructure is accentuated in Huntington's disease
por: Gregory, Sarah, et al.
Publicado: (2018)

Early white matter pathology in the fornix of the limbic system in Huntington disease
por: Gabery, Sanaz, et al.
Publicado: (2021)

Multiparametric characterization of white matter alterations in early stage Huntington disease
por: Adanyeguh, Isaac M., et al.
Publicado: (2021)

Progressive alterations in white matter microstructure across the timecourse of Huntington's disease
por: Estevez‐Fraga, Carlos, et al.
Publicado: (2023)

Therapeutic Effect of Berberine on Huntington’s Disease Transgenic Mouse Model
por: Jiang, Wenxiao, et al.
Publicado: (2015)

Fixel-Based Analysis Effectively Identifies White Matter Tract Degeneration in Huntington’s Disease
por: Oh, Sher Li, et al.
Publicado: (2021)

Timing of selective basal ganglia white matter loss in premanifest Huntington’s disease
por: Zeun, Paul, et al.
Publicado: (2022)

White matter cortico-striatal tracts predict apathy subtypes in Huntington's disease
por: De Paepe, Audrey E., et al.
Publicado: (2019)

Topological length of white matter connections predicts their rate of atrophy in premanifest Huntington’s disease
por: McColgan, Peter, et al.
Publicado: (2017)

White matter changes in Parkinson’s disease
por: Yang, Kai, et al.
Publicado: (2023)

New pathogenic insights from large animal models of neurodegenerative diseases
por: Yin, Peng, et al.
Publicado: (2022)

Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease
por: Yin, Peng, et al.
Publicado: (2020)

Brain Regions Showing White Matter Loss in Huntington’s Disease Are Enriched for Synaptic and Metabolic Genes
por: McColgan, Peter, et al.
Publicado: (2018)

Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice
por: Wang, Chuan-En, et al.
Publicado: (2010)

Therapeutic Strategies in Huntington’s Disease: From Genetic Defect to Gene Therapy
por: Jurcau, Anamaria, et al.
Publicado: (2022)

Stability of white matter changes related to Huntington’s disease in the presence of imaging noise: a DTI study
por: Müller, Hans-Peter, et al.
Publicado: (2011)

Robust MR-based approaches to quantifying white matter structure and structure/function alterations in Huntington's disease
por: Steventon, Jessica J., et al.
Publicado: (2016)

Voluntary saccade inhibition deficits correlate with extended white-matter cortico-basal atrophy in Huntington's disease
por: Vaca-Palomares, Israel, et al.
Publicado: (2017)

Mixed longitudinal and cross-sectional analyses of deep gray matter and white matter using diffusion weighted images in premanifest and manifest Huntington’s disease
por: Hu, Beini, et al.
Publicado: (2023)

Striatal spatial heterogeneity, clustering, and white matter association of GFAP(+) astrocytes in a mouse model of Huntington’s disease
por: Brown, Taylor G., et al.
Publicado: (2023)

Longitudinal in vivo MRI in a Huntington’s disease mouse model: Global atrophy in the absence of white matter microstructural damage
por: Steventon, Jessica J., et al.
Publicado: (2016)

Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington’s disease
por: Dridi, Haikel, et al.
Publicado: (2020)

Longitudinal multimodal MRI characterization of a knock-in mouse model of Huntington’s disease reveals early gray and white matter alterations
por: Pérot, Jean-Baptiste, et al.
Publicado: (2022)

Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
por: Garcia-Miralles, Marta, et al.
Publicado: (2016)

Irritability in Huntington’s Disease
por: Karagas, Nicholas E., et al.
Publicado: (2020)

White Matter Abnormalities and Animal Models Examining a Putative Role of Altered White Matter in Schizophrenia
por: Xu, Haiyun, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_jd0i2ilfhg13doadc0v42fr131