Cargando…

CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems

This paper is to discuss the potential of using CuZn in an electrical biosensor drug carrier for drug delivery systems. CuZn is the main semiconductor ingredient that has great promise as an electrochemical detector to trigger releases of active pharmaceutical ingredients (API). This CuZn biosensor...

Descripción completa

Detalles Bibliográficos
Autores principales: Lim, Yan Yik, Miskon, Azizi, Zaidi, Ahmad Mujahid Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656173/
https://www.ncbi.nlm.nih.gov/pubmed/36363264
http://dx.doi.org/10.3390/ma15217672
_version_ 1784829368103600128
author Lim, Yan Yik
Miskon, Azizi
Zaidi, Ahmad Mujahid Ahmad
author_facet Lim, Yan Yik
Miskon, Azizi
Zaidi, Ahmad Mujahid Ahmad
author_sort Lim, Yan Yik
collection PubMed
description This paper is to discuss the potential of using CuZn in an electrical biosensor drug carrier for drug delivery systems. CuZn is the main semiconductor ingredient that has great promise as an electrochemical detector to trigger releases of active pharmaceutical ingredients (API). This CuZn biosensor is produced with a green metal of frameworks, which is an anion node in conductive polymers linked by bioactive ligands using metal–polymerisation technology. The studies of Cu, Zn, and their oxides are highlighted by their electrochemical performance as electrical biosensors to electrically trigger API. The three main problems, which are glucose oxidisation, binding affinity, and toxicity, are highlighted, and their solutions are given. Moreover, their biocompatibilities, therapeutic efficacies, and drug delivery efficiencies are discussed with details given. Our three previous investigations of CuZn found results similar to those of other authors’ in terms of multiphases, polymerisation, and structure. This affirms that our research is on the right track, especially that related to green synthesis using plant extract, CuZn as a nanochip electric biosensor, and bioactive ligands to bind API, which are limited to the innermost circle of the non-enzymatic glucose sensor category.
format Online
Article
Text
id pubmed-9656173
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-96561732022-11-15 CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems Lim, Yan Yik Miskon, Azizi Zaidi, Ahmad Mujahid Ahmad Materials (Basel) Communication This paper is to discuss the potential of using CuZn in an electrical biosensor drug carrier for drug delivery systems. CuZn is the main semiconductor ingredient that has great promise as an electrochemical detector to trigger releases of active pharmaceutical ingredients (API). This CuZn biosensor is produced with a green metal of frameworks, which is an anion node in conductive polymers linked by bioactive ligands using metal–polymerisation technology. The studies of Cu, Zn, and their oxides are highlighted by their electrochemical performance as electrical biosensors to electrically trigger API. The three main problems, which are glucose oxidisation, binding affinity, and toxicity, are highlighted, and their solutions are given. Moreover, their biocompatibilities, therapeutic efficacies, and drug delivery efficiencies are discussed with details given. Our three previous investigations of CuZn found results similar to those of other authors’ in terms of multiphases, polymerisation, and structure. This affirms that our research is on the right track, especially that related to green synthesis using plant extract, CuZn as a nanochip electric biosensor, and bioactive ligands to bind API, which are limited to the innermost circle of the non-enzymatic glucose sensor category. MDPI 2022-11-01 /pmc/articles/PMC9656173/ /pubmed/36363264 http://dx.doi.org/10.3390/ma15217672 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Lim, Yan Yik
Miskon, Azizi
Zaidi, Ahmad Mujahid Ahmad
CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems
title CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems
title_full CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems
title_fullStr CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems
title_full_unstemmed CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems
title_short CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems
title_sort cuzn complex used in electrical biosensors for drug delivery systems
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656173/
https://www.ncbi.nlm.nih.gov/pubmed/36363264
http://dx.doi.org/10.3390/ma15217672
work_keys_str_mv AT limyanyik cuzncomplexusedinelectricalbiosensorsfordrugdeliverysystems
AT miskonazizi cuzncomplexusedinelectricalbiosensorsfordrugdeliverysystems
AT zaidiahmadmujahidahmad cuzncomplexusedinelectricalbiosensorsfordrugdeliverysystems