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CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems
This paper is to discuss the potential of using CuZn in an electrical biosensor drug carrier for drug delivery systems. CuZn is the main semiconductor ingredient that has great promise as an electrochemical detector to trigger releases of active pharmaceutical ingredients (API). This CuZn biosensor...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656173/ https://www.ncbi.nlm.nih.gov/pubmed/36363264 http://dx.doi.org/10.3390/ma15217672 |
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author | Lim, Yan Yik Miskon, Azizi Zaidi, Ahmad Mujahid Ahmad |
author_facet | Lim, Yan Yik Miskon, Azizi Zaidi, Ahmad Mujahid Ahmad |
author_sort | Lim, Yan Yik |
collection | PubMed |
description | This paper is to discuss the potential of using CuZn in an electrical biosensor drug carrier for drug delivery systems. CuZn is the main semiconductor ingredient that has great promise as an electrochemical detector to trigger releases of active pharmaceutical ingredients (API). This CuZn biosensor is produced with a green metal of frameworks, which is an anion node in conductive polymers linked by bioactive ligands using metal–polymerisation technology. The studies of Cu, Zn, and their oxides are highlighted by their electrochemical performance as electrical biosensors to electrically trigger API. The three main problems, which are glucose oxidisation, binding affinity, and toxicity, are highlighted, and their solutions are given. Moreover, their biocompatibilities, therapeutic efficacies, and drug delivery efficiencies are discussed with details given. Our three previous investigations of CuZn found results similar to those of other authors’ in terms of multiphases, polymerisation, and structure. This affirms that our research is on the right track, especially that related to green synthesis using plant extract, CuZn as a nanochip electric biosensor, and bioactive ligands to bind API, which are limited to the innermost circle of the non-enzymatic glucose sensor category. |
format | Online Article Text |
id | pubmed-9656173 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96561732022-11-15 CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems Lim, Yan Yik Miskon, Azizi Zaidi, Ahmad Mujahid Ahmad Materials (Basel) Communication This paper is to discuss the potential of using CuZn in an electrical biosensor drug carrier for drug delivery systems. CuZn is the main semiconductor ingredient that has great promise as an electrochemical detector to trigger releases of active pharmaceutical ingredients (API). This CuZn biosensor is produced with a green metal of frameworks, which is an anion node in conductive polymers linked by bioactive ligands using metal–polymerisation technology. The studies of Cu, Zn, and their oxides are highlighted by their electrochemical performance as electrical biosensors to electrically trigger API. The three main problems, which are glucose oxidisation, binding affinity, and toxicity, are highlighted, and their solutions are given. Moreover, their biocompatibilities, therapeutic efficacies, and drug delivery efficiencies are discussed with details given. Our three previous investigations of CuZn found results similar to those of other authors’ in terms of multiphases, polymerisation, and structure. This affirms that our research is on the right track, especially that related to green synthesis using plant extract, CuZn as a nanochip electric biosensor, and bioactive ligands to bind API, which are limited to the innermost circle of the non-enzymatic glucose sensor category. MDPI 2022-11-01 /pmc/articles/PMC9656173/ /pubmed/36363264 http://dx.doi.org/10.3390/ma15217672 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Lim, Yan Yik Miskon, Azizi Zaidi, Ahmad Mujahid Ahmad CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems |
title | CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems |
title_full | CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems |
title_fullStr | CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems |
title_full_unstemmed | CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems |
title_short | CuZn Complex Used in Electrical Biosensors for Drug Delivery Systems |
title_sort | cuzn complex used in electrical biosensors for drug delivery systems |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656173/ https://www.ncbi.nlm.nih.gov/pubmed/36363264 http://dx.doi.org/10.3390/ma15217672 |
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