Bufalin Inhibits Tumorigenesis, Stemness, and Epithelial–Mesenchymal Transition in Colorectal Cancer through a C-Kit/Slug Signaling Axis

Colorectal cancer (CRC) is a major source of morbidity and mortality, characterized by intratumoral heterogeneity and the presence of cancer stem cells (CSCs). Bufalin has potent activity against many tumors, but studies of its effect on CRC stemness are limited. We explored bufalin’s function and m...

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Detalles Bibliográficos
Autores principales: Ding, Ling, Yang, Yuning, Lu, Qin, Qu, Dongfeng, Chandrakesan, Parthasarathy, Feng, Hailan, Chen, Hong, Chen, Xuzheng, Liao, Zhuhui, Du, Jian, Cao, Zhiyun, Weygant, Nathaniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656328/
https://www.ncbi.nlm.nih.gov/pubmed/36362141
http://dx.doi.org/10.3390/ijms232113354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656328/
https://www.ncbi.nlm.nih.gov/pubmed/36362141
http://dx.doi.org/10.3390/ijms232113354

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