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Bufalin Inhibits Tumorigenesis, Stemness, and Epithelial–Mesenchymal Transition in Colorectal Cancer through a C-Kit/Slug Signaling Axis
Colorectal cancer (CRC) is a major source of morbidity and mortality, characterized by intratumoral heterogeneity and the presence of cancer stem cells (CSCs). Bufalin has potent activity against many tumors, but studies of its effect on CRC stemness are limited. We explored bufalin’s function and m...
Autores principales: | Ding, Ling, Yang, Yuning, Lu, Qin, Qu, Dongfeng, Chandrakesan, Parthasarathy, Feng, Hailan, Chen, Hong, Chen, Xuzheng, Liao, Zhuhui, Du, Jian, Cao, Zhiyun, Weygant, Nathaniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656328/ https://www.ncbi.nlm.nih.gov/pubmed/36362141 http://dx.doi.org/10.3390/ijms232113354 |
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