Synthesis and Biological Evaluation of New Isoxazolyl Steroids as Anti-Prostate Cancer Agents

Steroids with a nitrogen-containing heterocycle in the side chain are known as effective inhibitors of androgen signaling and/or testosterone biosynthesis, thus showing beneficial effects for the treatment of prostate cancer. In this work, a series of 3β-hydroxy-5-ene steroids, containing an isoxazo...

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Detalles Bibliográficos
Autores principales: Rudovich, Anton S., Peřina, Miroslav, Krech, Anastasiya V., Novozhilova, Maria Y., Tumilovich, Anastasia M., Shkel, Tatyana V., Grabovec, Irina P., Kvasnica, Miroslav, Mada, Lukáš, Zavialova, Maria G., Mekhtiev, Arif R., Jorda, Radek, Zhabinskii, Vladimir N., Khripach, Vladimir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656436/
https://www.ncbi.nlm.nih.gov/pubmed/36362320
http://dx.doi.org/10.3390/ijms232113534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656436/
https://www.ncbi.nlm.nih.gov/pubmed/36362320
http://dx.doi.org/10.3390/ijms232113534

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