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Alteration in the Synaptic and Extrasynaptic Organization of AMPA Receptors in the Hippocampus of P301S Tau Transgenic Mice

Tau pathology is a hallmark of Alzheimer’s disease (AD) and other tauopathies, but how pathological tau accumulation alters the glutamate receptor dynamics driving synaptic dysfunction is unclear. Here, we determined the impact of tau pathology on AMPAR expression, density, and subcellular distribut...

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Detalles Bibliográficos
Autores principales: Alfaro-Ruiz, Rocio, Aguado, Carolina, Martín-Belmonte, Alejandro, Moreno-Martínez, Ana Esther, Merchán-Rubira, Jesús, Hernández, Félix, Ávila, Jesús, Fukazawa, Yugo, Luján, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656470/
https://www.ncbi.nlm.nih.gov/pubmed/36362317
http://dx.doi.org/10.3390/ijms232113527