Cargando…

Pioglitazone Attenuates the Effects of Peripheral Inflammation in a Human In Vitro Blood–Brain Barrier Model

Biological mediators secreted during peripheral chronic inflammation reach the bloodstream and may damage the blood–brain barrier (BBB), triggering central nervous system (CNS) disorders. Full-fledged human BBB models are efficient tools to investigate pharmacological pathways and mechanisms of inju...

Descripción completa

Detalles Bibliográficos
Autores principales:	da Rocha, Gustavo Henrique Oliveira, Loiola, Rodrigo Azevedo, de Paula-Silva, Marina, Shimizu, Fumitaka, Kanda, Takashi, Vieira, Andrea, Gosselet, Fabien, Farsky, Sandra Helena Poliselli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656730/ https://www.ncbi.nlm.nih.gov/pubmed/36361571 http://dx.doi.org/10.3390/ijms232112781

Ejemplares similares

Pioglitazone-Mediated Attenuation of Experimental Colitis Relies on Cleaving of Annexin A1 Released by Macrophages
por: da Rocha, Gustavo Henrique Oliveira, et al.
Publicado: (2020)

TNFα Activates the Liver X Receptor Signaling Pathway and Promotes Cholesterol Efflux from Human Brain Pericytes Independently of ABCA1
por: Dib, Shiraz, et al.
Publicado: (2023)

Formyl Peptide Receptors and Annexin A1: Complementary Mechanisms to Infliximab in Murine Experimental Colitis and Crohn’s Disease
por: de Paula-Silva, Marina, et al.
Publicado: (2021)

Secretome of endothelial progenitor cells from stroke patients promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage
por: Loiola, Rodrigo Azevedo, et al.
Publicado: (2021)

Cellular and Molecular Mechanisms of Environmental Pollutants on Hematopoiesis
por: Scharf, Pablo, et al.
Publicado: (2020)

Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells
por: Heymans, Marjolein, et al.
Publicado: (2020)

Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance
por: Deligne, Clémence, et al.
Publicado: (2020)

Advancing human induced pluripotent stem cell‐derived blood‐brain barrier models for studying immune cell interactions
por: Nishihara, Hideaki, et al.
Publicado: (2020)

Ultrasmall cationic superparamagnetic iron oxide nanoparticles as nontoxic and efficient MRI contrast agent and magnetic-targeting tool
por: Uchiyama, Mayara Klimuk, et al.
Publicado: (2015)

Xenobiotics Delivered by Electronic Nicotine Delivery Systems: Potential Cellular and Molecular Mechanisms on the Pathogenesis of Chronic Kidney Disease
por: Scharf, Pablo, et al.
Publicado: (2022)

Highlighting In Vitro the Role of Brain-like Endothelial Cells on the Maturation and Metabolism of Brain Pericytes by SWATH Proteomics
por: Menaceur, Camille, et al.
Publicado: (2023)

Pioglitazone Attenuates Experimental Colitis-Associated Hyperalgesia through Improving the Intestinal Barrier Dysfunction
por: Huang, Yulin, et al.
Publicado: (2020)

Hydroquinone, an Environmental Pollutant, Affects Cartilage Homeostasis through the Activation of the Aryl Hydrocarbon Receptor Pathway
por: Heluany, Cintia Scucuglia, et al.
Publicado: (2023)

Pioglitazone Attenuates Vascular Fibrosis in Spontaneously Hypertensive Rats
por: Gao, Dengfeng, et al.
Publicado: (2012)

Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective
por: Kanhai, Anish A., et al.
Publicado: (2020)

Neutrophil depletion in the pre-implantation phase impairs pregnancy index, placenta and fetus development
por: Hebeda, Cristina Bichels, et al.
Publicado: (2022)

TNF-α and IL-1β Modulate Blood-Brain Barrier Permeability and Decrease Amyloid-β Peptide Efflux in a Human Blood-Brain Barrier Model
por: Versele, Romain, et al.
Publicado: (2022)

The restorative role of annexin A1 at the blood–brain barrier
por: McArthur, Simon, et al.
Publicado: (2016)

The Blood–Brain Barrier, an Evolving Concept Based on Technological Advances and Cell–Cell Communications
por: Menaceur, Camille, et al.
Publicado: (2021)

Fingolimod promotes blood–nerve barrier properties in vitro
por: Nishihara, Hideaki, et al.
Publicado: (2018)

Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles
por: Saint-Pol, Julien, et al.
Publicado: (2020)

Fingolimod Prevents Blood-Brain Barrier Disruption Induced by the Sera from Patients with Multiple Sclerosis
por: Nishihara, Hideaki, et al.
Publicado: (2015)

Effects of Different Peep Levels on Mesenteric Leukocyte-Endothelial Interactions in Rats During Mechanical Ventilation
por: Aikawa, Priscila, et al.
Publicado: (2009)

Effects of Long-Term Pioglitazone Treatment on Peripheral and Central Markers of Aging
por: Blalock, Eric M., et al.
Publicado: (2010)

Current clinical evidence on pioglitazone pharmacogenomics
por: Kawaguchi-Suzuki, Marina, et al.
Publicado: (2013)

Sera from Remitting and Secondary Progressive Multiple Sclerosis Patients Disrupt the Blood-Brain Barrier
por: Shimizu, Fumitaka, et al.
Publicado: (2014)

Pioglitazone Attenuates Cystic Burden in the PCK Rodent Model of Polycystic Kidney Disease
por: Blazer-Yost, Bonnie L., et al.
Publicado: (2010)

Pioglitazone attenuates kidney injury in an experimental model of gentamicin-induced nephrotoxicity in rats
por: Medić, Branislava, et al.
Publicado: (2019)

Long-term in vivo polychlorinated biphenyl 126 exposure induces oxidative stress and alters proteomic profile on islets of Langerhans
por: Loiola, Rodrigo Azevedo, et al.
Publicado: (2016)

Markedly Increased IP-10 Production by Blood-Brain Barrier in Neuromyelitis Optica
por: Shimizu, Fumitaka, et al.
Publicado: (2015)

Blood–Nerve Barrier (BNB) Pathology in Diabetic Peripheral Neuropathy and In Vitro Human BNB Model
por: Takeshita, Yukio, et al.
Publicado: (2020)

Severity and Patterns of Blood-Nerve Barrier Breakdown in Patients with Chronic Inflammatory Demyelinating Polyradiculoneuropathy: Correlations with Clinical Subtypes
por: Shimizu, Fumitaka, et al.
Publicado: (2014)

Pioglitazone: Indian perspective
por: Shukla, Rishi, et al.
Publicado: (2011)

Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells
por: Hong, Seok-Woo, et al.
Publicado: (2018)

Mechanisms of the effectiveness of poly(ε-caprolactone) lipid-core nanocapsules loaded with methotrexate on glioblastoma multiforme treatment
por: Pereira, Natalia Rubio Claret, et al.
Publicado: (2018)

Impact of Pesticide Residues on the Gut-Microbiota–Blood–Brain Barrier Axis: A Narrative Review
por: Abou Diwan, Maria, et al.
Publicado: (2023)

Annexin A1/Formyl Peptide Receptor Pathway Controls Uterine Receptivity to the Blastocyst
por: Hebeda, Cristina B., et al.
Publicado: (2020)

The Role of Annexin A1 in DNA Damage Response in Placental Cells: Impact on Gestational Diabetes Mellitus
por: Moreli, Jusciele Brogin, et al.
Publicado: (2023)

Pioglitazone Attenuates Drug-Eluting Stent-Induced Proinflammatory State in Patients by Blocking Ubiquitination of PPAR
por: Wang, Zhongxia, et al.
Publicado: (2016)

Transport study of interleukin-1 inhibitors using a human in vitro model of the blood-brain barrier
por: Sjöström, Elisabet O., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_llbitoelcqbepg0n58vf10bmj0