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Structural Insight into TNIK Inhibition

TRAF2- and NCK-interacting kinase (TNIK) has emerged as a promising therapeutic target for colorectal cancer because of its essential role in regulating the Wnt/β-catenin signaling pathway. Colorectal cancers contain many mutations in the Wnt/β-catenin signaling pathway genes upstream of TNIK, such...

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Detalles Bibliográficos
Autores principales:	Kukimoto-Niino, Mutsuko, Shirouzu, Mikako, Yamada, Tesshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656744/ https://www.ncbi.nlm.nih.gov/pubmed/36361804 http://dx.doi.org/10.3390/ijms232113010

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