Cargando…
Effective, Long-Term, Neutrophil Depletion Using a Murinized Anti-Ly-6G 1A8 Antibody
Neutrophils are crucial innate immune cells but also play key roles in various diseases, such as cancer, where they can perform both pro- and anti-tumorigenic functions. To study the function of neutrophils in vivo, these cells are often depleted using Ly-6G or Gr-1 depleting antibodies or genetic “...
Autores principales: | Olofsen, Patricia A., Stip, Marjolein C., Jansen, J. H. Marco, Chan, Chilam, Nederend, Maaike, Tieland, Ralph G., Tsioumpekou, Maria, Leusen, Jeanette H. W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656769/ https://www.ncbi.nlm.nih.gov/pubmed/36359801 http://dx.doi.org/10.3390/cells11213406 |
Ejemplares similares
-
Characterization of human Fc alpha receptor transgenic mice: comparison of CD89 expression and antibody-dependent tumor killing between mouse strains
por: Stip, Marjolein C., et al.
Publicado: (2023) -
Anti-GD2 IgA kills tumors by neutrophils without antibody-associated pain in the preclinical treatment of high-risk neuroblastoma
por: Evers, Mitchell, et al.
Publicado: (2021) -
The Role of Cytokines in Neutrophil Development, Tissue Homing, Function and Plasticity in Health and Disease
por: Tsioumpekou, Maria, et al.
Publicado: (2023) -
Fc Engineering Strategies to Advance IgA Antibodies as Therapeutic Agents
por: van Tetering, Geert, et al.
Publicado: (2020) -
Ly6G-mediated depletion of neutrophils is dependent on macrophages
por: Bruhn, Kevin W., et al.
Publicado: (2015)