Loss of the Nuclear Envelope Protein LAP1B Disrupts the Myogenic Differentiation of Patient-Derived Fibroblasts

Lamina-associated polypeptide 1 (LAP1) is a ubiquitously expressed inner nuclear membrane protein encoded by TOR1AIP1, and presents as two isoforms in humans, LAP1B and LAP1C. While loss of both isoforms results in a multisystemic progeroid-like syndrome, specific loss of LAP1B causes muscular dystr...

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Detalles Bibliográficos
Autores principales: Kayman Kürekçi, Gülsüm, Acar, Aybar C., Dinçer, Pervin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656778/
https://www.ncbi.nlm.nih.gov/pubmed/36362402
http://dx.doi.org/10.3390/ijms232113615

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