Real-World Study: A Powerful Tool for Malignant Tumor Research in General Surgery

SIMPLE SUMMARY: In the context of today’s “accurate” medical care, the disadvantages of traditional randomized controlled trials have become increasingly prominent. At the same time, real-world study is more and more respected by people. Therefore, the purpose of this paper is to review the application of real-world study in the treatment of malignant tumors in general surgery in the past three years, to provide real-world evidence for clinical diagnosis and treatment. More importantly, while summarizing the existing research results, this paper also puts forward the current shortcomings and prospects of real-world study, which will contribute to further research, to provide help for the treatment of malignant tumors in general surgery. ABSTRACT: Real-world study (RWS) is a method to draw conclusions by collecting and analyzing real-world data under a real clinical background. Compared with traditional randomized controlled trials (RCTs), RWSs are favored by clinicians because of their low cost and good extrapolation. In recent years, RWS has made remarkable achievements in the field of general surgery, especially in the drug treatment of advanced malignant tumors. Therefore, to further understand the main contents of the existing RWS and the application prospect of RWS in the future, this paper systematically reviews the clinical application of RWS in malignant tumors in general surgery in the past three years.