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Structure-Based Discovery and Biological Assays of a Novel PRMT5 Inhibitor for Non-Small Cell Lung Cancer

Protein arginine methyltransferase 5 (PRMT5) is a popular anticancer target that regulates histone or nonhistone methylation and is linked to the development and poor prognosis of non-small cell lung cancer. PRMT5 inhibitors have shown great promise in clinical trials as a cancer therapy. However, m...

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Detalles Bibliográficos
Autores principales:	Chen, Yingqing, Zhang, Mingyu, Wu, Anxin, Yao, Xiaojun, Wang, Qianqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9656811/ https://www.ncbi.nlm.nih.gov/pubmed/36364261 http://dx.doi.org/10.3390/molecules27217436

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