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Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study
Stress shielding secondary to bone resorption is one of the main causes of aseptic loosening, which limits the lifespan of the hip prostheses and increases the rates of revision surgery. This study proposes a low stiffness polyether–ether–ketone (PEEK) hip prostheses, produced by fused deposition mo...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657056/ https://www.ncbi.nlm.nih.gov/pubmed/36365594 http://dx.doi.org/10.3390/polym14214600 |
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author | Naghavi, Seyed Ataollah Lin, Churun Sun, Changning Tamaddon, Maryam Basiouny, Mariam Garcia-Souto, Pilar Taylor, Stephen Hua, Jia Li, Dichen Wang, Ling Liu, Chaozong |
author_facet | Naghavi, Seyed Ataollah Lin, Churun Sun, Changning Tamaddon, Maryam Basiouny, Mariam Garcia-Souto, Pilar Taylor, Stephen Hua, Jia Li, Dichen Wang, Ling Liu, Chaozong |
author_sort | Naghavi, Seyed Ataollah |
collection | PubMed |
description | Stress shielding secondary to bone resorption is one of the main causes of aseptic loosening, which limits the lifespan of the hip prostheses and increases the rates of revision surgery. This study proposes a low stiffness polyether–ether–ketone (PEEK) hip prostheses, produced by fused deposition modelling to minimize the stress difference after the hip replacement. The stress shielding effect and the potential bone resorption of the PEEK implant was investigated through both experimental tests and FE simulation. A generic Ti6Al4V implant was incorporated in this study to allow fair comparison as control group. Attributed to the low stiffness, the proposed PEEK implant showed a more natural stress distribution, less stress shielding (by 104%), and loss in bone mass (by 72%) compared with the Ti6Al4V implant. The stiffness of the Ti6Al4V and the PEEK implant were measured through compression tests to be 2.76 kN/mm and 0.276 kN/mm. The factor of safety for the PEEK implant in both static and dynamic loading scenarios were obtained through simulation. Most of the regions in the PEEK implant were tested to be safe (FoS larger than 1) in terms of representing daily activities (2300 N), while the medial neck and distal restriction point of the implant attracts large von Mises stress 82 MPa and 76 MPa, respectively, and, thus, may possibly fail during intensive activities by yield and fatigue. Overall, considering the reduction in stress shielding and bone resorption in cortical bone, PEEK could be a promising material for the patient–specific femoral implants. |
format | Online Article Text |
id | pubmed-9657056 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-96570562022-11-15 Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study Naghavi, Seyed Ataollah Lin, Churun Sun, Changning Tamaddon, Maryam Basiouny, Mariam Garcia-Souto, Pilar Taylor, Stephen Hua, Jia Li, Dichen Wang, Ling Liu, Chaozong Polymers (Basel) Article Stress shielding secondary to bone resorption is one of the main causes of aseptic loosening, which limits the lifespan of the hip prostheses and increases the rates of revision surgery. This study proposes a low stiffness polyether–ether–ketone (PEEK) hip prostheses, produced by fused deposition modelling to minimize the stress difference after the hip replacement. The stress shielding effect and the potential bone resorption of the PEEK implant was investigated through both experimental tests and FE simulation. A generic Ti6Al4V implant was incorporated in this study to allow fair comparison as control group. Attributed to the low stiffness, the proposed PEEK implant showed a more natural stress distribution, less stress shielding (by 104%), and loss in bone mass (by 72%) compared with the Ti6Al4V implant. The stiffness of the Ti6Al4V and the PEEK implant were measured through compression tests to be 2.76 kN/mm and 0.276 kN/mm. The factor of safety for the PEEK implant in both static and dynamic loading scenarios were obtained through simulation. Most of the regions in the PEEK implant were tested to be safe (FoS larger than 1) in terms of representing daily activities (2300 N), while the medial neck and distal restriction point of the implant attracts large von Mises stress 82 MPa and 76 MPa, respectively, and, thus, may possibly fail during intensive activities by yield and fatigue. Overall, considering the reduction in stress shielding and bone resorption in cortical bone, PEEK could be a promising material for the patient–specific femoral implants. MDPI 2022-10-29 /pmc/articles/PMC9657056/ /pubmed/36365594 http://dx.doi.org/10.3390/polym14214600 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Naghavi, Seyed Ataollah Lin, Churun Sun, Changning Tamaddon, Maryam Basiouny, Mariam Garcia-Souto, Pilar Taylor, Stephen Hua, Jia Li, Dichen Wang, Ling Liu, Chaozong Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study |
title | Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study |
title_full | Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study |
title_fullStr | Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study |
title_full_unstemmed | Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study |
title_short | Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study |
title_sort | stress shielding and bone resorption of press-fit polyether–ether–ketone (peek) hip prosthesis: a sawbone model study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657056/ https://www.ncbi.nlm.nih.gov/pubmed/36365594 http://dx.doi.org/10.3390/polym14214600 |
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