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Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study

Stress shielding secondary to bone resorption is one of the main causes of aseptic loosening, which limits the lifespan of the hip prostheses and increases the rates of revision surgery. This study proposes a low stiffness polyether–ether–ketone (PEEK) hip prostheses, produced by fused deposition mo...

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Autores principales: Naghavi, Seyed Ataollah, Lin, Churun, Sun, Changning, Tamaddon, Maryam, Basiouny, Mariam, Garcia-Souto, Pilar, Taylor, Stephen, Hua, Jia, Li, Dichen, Wang, Ling, Liu, Chaozong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657056/
https://www.ncbi.nlm.nih.gov/pubmed/36365594
http://dx.doi.org/10.3390/polym14214600
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author Naghavi, Seyed Ataollah
Lin, Churun
Sun, Changning
Tamaddon, Maryam
Basiouny, Mariam
Garcia-Souto, Pilar
Taylor, Stephen
Hua, Jia
Li, Dichen
Wang, Ling
Liu, Chaozong
author_facet Naghavi, Seyed Ataollah
Lin, Churun
Sun, Changning
Tamaddon, Maryam
Basiouny, Mariam
Garcia-Souto, Pilar
Taylor, Stephen
Hua, Jia
Li, Dichen
Wang, Ling
Liu, Chaozong
author_sort Naghavi, Seyed Ataollah
collection PubMed
description Stress shielding secondary to bone resorption is one of the main causes of aseptic loosening, which limits the lifespan of the hip prostheses and increases the rates of revision surgery. This study proposes a low stiffness polyether–ether–ketone (PEEK) hip prostheses, produced by fused deposition modelling to minimize the stress difference after the hip replacement. The stress shielding effect and the potential bone resorption of the PEEK implant was investigated through both experimental tests and FE simulation. A generic Ti6Al4V implant was incorporated in this study to allow fair comparison as control group. Attributed to the low stiffness, the proposed PEEK implant showed a more natural stress distribution, less stress shielding (by 104%), and loss in bone mass (by 72%) compared with the Ti6Al4V implant. The stiffness of the Ti6Al4V and the PEEK implant were measured through compression tests to be 2.76 kN/mm and 0.276 kN/mm. The factor of safety for the PEEK implant in both static and dynamic loading scenarios were obtained through simulation. Most of the regions in the PEEK implant were tested to be safe (FoS larger than 1) in terms of representing daily activities (2300 N), while the medial neck and distal restriction point of the implant attracts large von Mises stress 82 MPa and 76 MPa, respectively, and, thus, may possibly fail during intensive activities by yield and fatigue. Overall, considering the reduction in stress shielding and bone resorption in cortical bone, PEEK could be a promising material for the patient–specific femoral implants.
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spelling pubmed-96570562022-11-15 Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study Naghavi, Seyed Ataollah Lin, Churun Sun, Changning Tamaddon, Maryam Basiouny, Mariam Garcia-Souto, Pilar Taylor, Stephen Hua, Jia Li, Dichen Wang, Ling Liu, Chaozong Polymers (Basel) Article Stress shielding secondary to bone resorption is one of the main causes of aseptic loosening, which limits the lifespan of the hip prostheses and increases the rates of revision surgery. This study proposes a low stiffness polyether–ether–ketone (PEEK) hip prostheses, produced by fused deposition modelling to minimize the stress difference after the hip replacement. The stress shielding effect and the potential bone resorption of the PEEK implant was investigated through both experimental tests and FE simulation. A generic Ti6Al4V implant was incorporated in this study to allow fair comparison as control group. Attributed to the low stiffness, the proposed PEEK implant showed a more natural stress distribution, less stress shielding (by 104%), and loss in bone mass (by 72%) compared with the Ti6Al4V implant. The stiffness of the Ti6Al4V and the PEEK implant were measured through compression tests to be 2.76 kN/mm and 0.276 kN/mm. The factor of safety for the PEEK implant in both static and dynamic loading scenarios were obtained through simulation. Most of the regions in the PEEK implant were tested to be safe (FoS larger than 1) in terms of representing daily activities (2300 N), while the medial neck and distal restriction point of the implant attracts large von Mises stress 82 MPa and 76 MPa, respectively, and, thus, may possibly fail during intensive activities by yield and fatigue. Overall, considering the reduction in stress shielding and bone resorption in cortical bone, PEEK could be a promising material for the patient–specific femoral implants. MDPI 2022-10-29 /pmc/articles/PMC9657056/ /pubmed/36365594 http://dx.doi.org/10.3390/polym14214600 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Naghavi, Seyed Ataollah
Lin, Churun
Sun, Changning
Tamaddon, Maryam
Basiouny, Mariam
Garcia-Souto, Pilar
Taylor, Stephen
Hua, Jia
Li, Dichen
Wang, Ling
Liu, Chaozong
Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study
title Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study
title_full Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study
title_fullStr Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study
title_full_unstemmed Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study
title_short Stress Shielding and Bone Resorption of Press-Fit Polyether–Ether–Ketone (PEEK) Hip Prosthesis: A Sawbone Model Study
title_sort stress shielding and bone resorption of press-fit polyether–ether–ketone (peek) hip prosthesis: a sawbone model study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657056/
https://www.ncbi.nlm.nih.gov/pubmed/36365594
http://dx.doi.org/10.3390/polym14214600
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