Genetic Deletion of Mmp9 Does Not Reduce Airway Inflammation and Structural Lung Damage in Mice with Cystic Fibrosis-like Lung Disease

Elevated levels of matrix metalloprotease 9 (MMP-9) and neutrophil elastase (NE) are associated with bronchiectasis and lung function decline in patients with cystic fibrosis (CF). MMP-9 is a potent extracellular matrix-degrading enzyme which is activated by NE and has been implicated in structural...

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Detalles Bibliográficos
Autores principales: Wagner, Claudius, Balázs, Anita, Schatterny, Jolanthe, Zhou-Suckow, Zhe, Duerr, Julia, Schultz, Carsten, Mall, Marcus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657231/
https://www.ncbi.nlm.nih.gov/pubmed/36362203
http://dx.doi.org/10.3390/ijms232113405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657231/
https://www.ncbi.nlm.nih.gov/pubmed/36362203
http://dx.doi.org/10.3390/ijms232113405

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