Comparison of EMT-Related and Multi-Drug Resistant Gene Expression, Extracellular Matrix Production, and Drug Sensitivity in NSCLC Spheroids Generated by Scaffold-Free and Scaffold-Based Methods

Multicellular 3D tumor models are becoming a powerful tool for testing of novel drug products and personalized anticancer therapy. Tumor spheroids, a commonly used 3D multicellular tumor model, more closely reproduce the tumor microenvironment than conventional 2D cell cultures. It should be noted t...

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Detalles Bibliográficos
Autores principales: Qi, Xiaoli, Prokhorova, Alexandra V., Mezentsev, Alexander V., Shen, Ningfei, Trofimenko, Alexander V., Filkov, Gleb I., Sulimanov, Rushan A., Makarov, Vladimir A., Durymanov, Mikhail O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657250/
https://www.ncbi.nlm.nih.gov/pubmed/36362093
http://dx.doi.org/10.3390/ijms232113306

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