Cargando…

Comprehensive Characterization of the Regulatory Landscape of Adrenocortical Carcinoma: Novel Transcription Factors and Targets Associated with Prognosis

SIMPLE SUMMARY: Adult adrenocortical carcinoma (ACC) is a rare and aggressive tumor in adults, usually associated with excessive steroid secretion. It is highly metastatic and has few therapeutic options and a poor prognosis. Here, we explore the hallmarks of ACC influenced by transcription factors...

Descripción completa

Detalles Bibliográficos
Autores principales:	Muzzi, João C. D., Magno, Jéssica M., Souza, Jean S., Alvarenga, Larissa M., de Moura, Juliana F., Figueiredo, Bonald C., Castro, Mauro A. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657296/ https://www.ncbi.nlm.nih.gov/pubmed/36358698 http://dx.doi.org/10.3390/cancers14215279

Ejemplares similares

Adrenocortical Carcinoma Steroid Profiles: In Silico Pan-Cancer Analysis of TCGA Data Uncovers Immunotherapy Targets for Potential Improved Outcomes
por: Muzzi, João C. D., et al.
Publicado: (2021)

Steroidogenic Factor 1, a Goldilocks Transcription Factor from Adrenocortical Organogenesis to Malignancy
por: Relav, Lauriane, et al.
Publicado: (2023)

Genomic landscape of pediatric adrenocortical tumors
por: Pinto, Emilia M., et al.
Publicado: (2015)

Pediatric Adrenocortical Tumors: What They Can Tell Us on Adrenal Development and Comparison with Adult Adrenal Tumors
por: Lalli, Enzo, et al.
Publicado: (2015)

PSUN13 Transcriptional and epigenetic landscapes of adrenocortical tumors
por: Lerario, Antonio, et al.
Publicado: (2022)

The Immunotherapy Landscape in Adrenocortical Cancer
por: Pegna, Guillaume J., et al.
Publicado: (2021)

Germline Variants in Phosphodiesterase Genes and Genetic Predisposition to Pediatric Adrenocortical Tumors
por: Pinto, Emilia Modolo, et al.
Publicado: (2020)

Integrative analysis of SF-1 transcription factor dosage impact on genome-wide binding and gene expression regulation
por: Doghman, Mabrouka, et al.
Publicado: (2013)

MicroRNA Era: The Importance for Diagnosis and Prognosis of Adrenocortical Tumors
por: Bezerra, João Evangelista, et al.
Publicado: (2014)

Adrenocortical Activity in Disseminated Malignant Disease in Relation to Prognosis
por: Bishop, M. C., et al.
Publicado: (1970)

Adrenocortical carcinoma (ACC): diagnosis, prognosis, and treatment
por: Libé, Rossella
Publicado: (2015)

Metastatic and recurrent adrenocortical cancer is not defined by its genomic landscape
por: Fojo, Tito, et al.
Publicado: (2020)

Nuclear DNA content and morphological characteristics in the prognosis of adrenocortical carcinoma.
por: Haak, H. R., et al.
Publicado: (1993)

An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis
por: Xiang, Guanjue, et al.
Publicado: (2020)

Comprehensive transcriptional landscape of aging mouse liver
por: White, Ryan R., et al.
Publicado: (2015)

Molecular markers of prognosis in canine cortisol‐secreting adrenocortical tumours
por: Sanders, Karin, et al.
Publicado: (2019)

A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence
por: Surakhy, Mirvat, et al.
Publicado: (2020)

The Role of Immunohistochemical Markers for the Diagnosis and Prognosis of Adrenocortical Neoplasms
por: Angelousi, Anna, et al.
Publicado: (2021)

Transcriptome in paraffin samples for the diagnosis and prognosis of adrenocortical carcinoma
por: Jouinot, Anne, et al.
Publicado: (2022)

The genome-wide transcriptional regulatory landscape of ecdysone in the silkworm
por: Cheng, Dong, et al.
Publicado: (2018)

Need for Comprehensive Hormonal Workup in the Management of Adrenocortical Tumors in Children
por: Gönç, E. Nazlı, et al.
Publicado: (2014)

Cancer Stemness Associated With Prognosis and the Efficacy of Immunotherapy in Adrenocortical Carcinoma
por: Shi, Xiaoxi, et al.
Publicado: (2021)

The prognosis difference between elderly and younger patients with adrenocortical carcinoma
por: He, Shengyin, et al.
Publicado: (2023)

Histological scores and tumor size on stage II in adrenocortical carcinomas
por: Oliveira, Rui Caetano, et al.
Publicado: (2021)

The regulatory and transcriptional landscape associated with carbon utilization in a filamentous fungus
por: Wu, Vincent W., et al.
Publicado: (2020)

Recurrent Amplification of the Osmotic Stress Transcription Factor NFAT5 in Adrenocortical Carcinoma
por: Brown, Taylor C, et al.
Publicado: (2020)

The neutrophil-to-lymphocyte ratio (NLR) predicts adrenocortical carcinoma and is correlated with the prognosis
por: Mochizuki, Taku, et al.
Publicado: (2017)

Interplay between glucocorticoids and tumor-infiltrating lymphocytes on the prognosis of adrenocortical carcinoma
por: Landwehr, Laura-Sophie, et al.
Publicado: (2020)

ELISA for Determination of Human Growth Hormone: Recognition of Helix 4 Epitopes
por: Moura, Juliana F., et al.
Publicado: (2004)

Cancer-testis Antigen FATE1 Expression in Adrenocortical Tumors Is Associated with A Pervasive Autoimmune Response and Is A Marker of Malignancy in Adult, but Not Children, ACC
por: Doghman-Bouguerra, Mabrouka, et al.
Publicado: (2020)

Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme
por: Chu, Tinyi, et al.
Publicado: (2018)

Genetic, transcriptional, and regulatory landscape of monolignol biosynthesis pathway in Miscanthus × giganteus
por: Zeng, Xiaofei, et al.
Publicado: (2020)

A post-transcriptional regulatory landscape of aging in the female mouse hippocampus
por: Winsky-Sommerer, Raphaelle, et al.
Publicado: (2023)

Landscape and perturbation of enhancer-driven core transcription regulatory circuits in cancer
por: Xu, Juan, et al.
Publicado: (2023)

Extension of Adrenocortical Carcinoma into the Right Atrium
por: Castro-Dominguez, Yulanka, et al.
Publicado: (2017)

Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells
por: De Simone, Marco, et al.
Publicado: (2016)

Pediatric adrenocortical carcinoma
por: Ilanchezhian, Maran, et al.
Publicado: (2022)

Specific Immunoassays for Placental Alkaline Phosphatase As a Tumor Marker
por: Stinghen, Sérvio T., et al.
Publicado: (2006)

Comprehensive immunogenomic landscape analysis of prognosis-related genes in head and neck cancer
por: Li, Lei, et al.
Publicado: (2020)

Comprehensive Analysis of the Transcriptional and Mutational Landscape of Follicular and Papillary Thyroid Cancers
por: Yoo, Seong-Keun, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_gf9lrh8mpt629s0fpj2uksufh2