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Alu Deletions in LAMA2 and CDH4 Genes Are Key Components of Polygenic Predictors of Longevity

Longevity is a unique human phenomenon and a highly stable trait, characterized by polygenicity. The longevity phenotype occurs due to the ability to successfully withstand the age-related genomic instability triggered by Alu elements. The purpose of our cross-sectional study was to evaluate the com...

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Detalles Bibliográficos
Autores principales: Erdman, Vera V., Karimov, Denis D., Tuktarova, Ilsia A., Timasheva, Yanina R., Nasibullin, Timur R., Korytina, Gulnaz F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657309/
https://www.ncbi.nlm.nih.gov/pubmed/36362280
http://dx.doi.org/10.3390/ijms232113492