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A Mini Review on Osteoporosis: From Biology to Pharmacological Management of Bone Loss

Osteoporosis refers to excessive bone loss as reflected by the deterioration of bone mass and microarchitecture, which compromises bone strength. It is a complex multifactorial endocrine disease. Its pathogenesis relies on the presence of several endogenous and exogenous risk factors, which skew the...

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Autores principales: Chin, Kok-Yong, Ng, Ben Nett, Rostam, Muhd Khairik Imran, Muhammad Fadzil, Nur Farah Dhaniyah, Raman, Vaishnavi, Mohamed Yunus, Farzana, Syed Hashim, Syed Alhafiz, Ekeuku, Sophia Ogechi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657533/
https://www.ncbi.nlm.nih.gov/pubmed/36362662
http://dx.doi.org/10.3390/jcm11216434
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author Chin, Kok-Yong
Ng, Ben Nett
Rostam, Muhd Khairik Imran
Muhammad Fadzil, Nur Farah Dhaniyah
Raman, Vaishnavi
Mohamed Yunus, Farzana
Syed Hashim, Syed Alhafiz
Ekeuku, Sophia Ogechi
author_facet Chin, Kok-Yong
Ng, Ben Nett
Rostam, Muhd Khairik Imran
Muhammad Fadzil, Nur Farah Dhaniyah
Raman, Vaishnavi
Mohamed Yunus, Farzana
Syed Hashim, Syed Alhafiz
Ekeuku, Sophia Ogechi
author_sort Chin, Kok-Yong
collection PubMed
description Osteoporosis refers to excessive bone loss as reflected by the deterioration of bone mass and microarchitecture, which compromises bone strength. It is a complex multifactorial endocrine disease. Its pathogenesis relies on the presence of several endogenous and exogenous risk factors, which skew the physiological bone remodelling to a more catabolic process that results in net bone loss. This review aims to provide an overview of osteoporosis from its biology, epidemiology and clinical aspects (detection and pharmacological management). The review will serve as an updated reference for readers to understand the basics of osteoporosis and take action to prevent and manage this disease.
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spelling pubmed-96575332022-11-15 A Mini Review on Osteoporosis: From Biology to Pharmacological Management of Bone Loss Chin, Kok-Yong Ng, Ben Nett Rostam, Muhd Khairik Imran Muhammad Fadzil, Nur Farah Dhaniyah Raman, Vaishnavi Mohamed Yunus, Farzana Syed Hashim, Syed Alhafiz Ekeuku, Sophia Ogechi J Clin Med Review Osteoporosis refers to excessive bone loss as reflected by the deterioration of bone mass and microarchitecture, which compromises bone strength. It is a complex multifactorial endocrine disease. Its pathogenesis relies on the presence of several endogenous and exogenous risk factors, which skew the physiological bone remodelling to a more catabolic process that results in net bone loss. This review aims to provide an overview of osteoporosis from its biology, epidemiology and clinical aspects (detection and pharmacological management). The review will serve as an updated reference for readers to understand the basics of osteoporosis and take action to prevent and manage this disease. MDPI 2022-10-30 /pmc/articles/PMC9657533/ /pubmed/36362662 http://dx.doi.org/10.3390/jcm11216434 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chin, Kok-Yong
Ng, Ben Nett
Rostam, Muhd Khairik Imran
Muhammad Fadzil, Nur Farah Dhaniyah
Raman, Vaishnavi
Mohamed Yunus, Farzana
Syed Hashim, Syed Alhafiz
Ekeuku, Sophia Ogechi
A Mini Review on Osteoporosis: From Biology to Pharmacological Management of Bone Loss
title A Mini Review on Osteoporosis: From Biology to Pharmacological Management of Bone Loss
title_full A Mini Review on Osteoporosis: From Biology to Pharmacological Management of Bone Loss
title_fullStr A Mini Review on Osteoporosis: From Biology to Pharmacological Management of Bone Loss
title_full_unstemmed A Mini Review on Osteoporosis: From Biology to Pharmacological Management of Bone Loss
title_short A Mini Review on Osteoporosis: From Biology to Pharmacological Management of Bone Loss
title_sort mini review on osteoporosis: from biology to pharmacological management of bone loss
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657533/
https://www.ncbi.nlm.nih.gov/pubmed/36362662
http://dx.doi.org/10.3390/jcm11216434
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