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CXCL8 Up-Regulated LSECtin through AKT Signal and Correlates with the Immune Microenvironment Modulation in Colon Cancer

SIMPLE SUMMARY: Patients with high expression of CXCL8 are not sensitive to immune checkpoint inhibitors (ICIs) treatment, but the mechanism is unclear. LSECtin is the immune checkpoint ligand of LAG3, and is considered as an important factor of ICIs resistance. This study confirmed the role of CXCL...

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Detalles Bibliográficos
Autores principales:	Fang, Shaojun, Cheng, Xianshuo, Shen, Tao, Dong, Jian, Li, Yunfeng, Li, Zhenhui, Tian, Linghan, Zhang, Yangwei, Pan, Xueyan, Yin, Zhengfeng, Yang, Zhibin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657600/ https://www.ncbi.nlm.nih.gov/pubmed/36358719 http://dx.doi.org/10.3390/cancers14215300

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