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Ibrutinib Prevents Acute Lung Injury via Multi-Targeting BTK, FLT3 and EGFR in Mice

Ibrutinib has potential therapeutic or protective effects against viral- and bacterial-induced acute lung injury (ALI), likely by modulating the Bruton tyrosine kinase (BTK) signaling pathway. However, ibrutinib has multi-target effects. Moreover, immunity and inflammation targets in ALI treatment a...

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Detalles Bibliográficos
Autores principales: Rao, Huanan, Song, Xiaominting, Lei, Jieting, Lu, Peng, Zhao, Guiying, Kang, Xin, Zhang, Duanna, Zhang, Tingrui, Ren, Yali, Peng, Cheng, Li, Yuzhi, Pei, Jin, Cao, Zhixing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657648/
https://www.ncbi.nlm.nih.gov/pubmed/36362264
http://dx.doi.org/10.3390/ijms232113478