Cargando…
Ibrutinib Prevents Acute Lung Injury via Multi-Targeting BTK, FLT3 and EGFR in Mice
Ibrutinib has potential therapeutic or protective effects against viral- and bacterial-induced acute lung injury (ALI), likely by modulating the Bruton tyrosine kinase (BTK) signaling pathway. However, ibrutinib has multi-target effects. Moreover, immunity and inflammation targets in ALI treatment a...
Autores principales: | Rao, Huanan, Song, Xiaominting, Lei, Jieting, Lu, Peng, Zhao, Guiying, Kang, Xin, Zhang, Duanna, Zhang, Tingrui, Ren, Yali, Peng, Cheng, Li, Yuzhi, Pei, Jin, Cao, Zhixing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657648/ https://www.ncbi.nlm.nih.gov/pubmed/36362264 http://dx.doi.org/10.3390/ijms232113478 |
Ejemplares similares
-
Neoprzewaquinone A Inhibits Breast Cancer Cell Migration and Promotes Smooth Muscle Relaxation by Targeting PIM1 to Block ROCK2/STAT3 Pathway
por: Zhao, Guiying, et al.
Publicado: (2023) -
Ibrutinib and novel BTK inhibitors in clinical development
por: Akinleye, Akintunde, et al.
Publicado: (2013) -
A Review of the Pharmacological Properties of Psoralen
por: Ren, Yali, et al.
Publicado: (2020) -
Ibrutinib Inhibits Angiogenesis and Tumorigenesis in a BTK-Independent Manner
por: Liu, Jia, et al.
Publicado: (2022) -
Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance
por: Naeem, Aishath, et al.
Publicado: (2022)