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Pioglitazone Modifies Kupffer Cell Function and Protects against Escherichia coli-Induced Bacteremia in Burned Mice

Infectious complications and subsequent sepsis in severely burned patients lead to high morbidity and mortality in response to uncontrolled innate immune responses mediated by macrophages. Peroxisome proliferator-activated receptor gamma (PPARγ) has anti-inflammatory activity and acts as a master re...

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Detalles Bibliográficos
Autores principales: Miyazaki, Hiromi, Kinoshita, Manabu, Nakashima, Hiroyuki, Nakamura, Shingo, Saitoh, Daizoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657905/
https://www.ncbi.nlm.nih.gov/pubmed/36361535
http://dx.doi.org/10.3390/ijms232112746