Enhancing an Oxidative “Trojan Horse” Action of Vitamin C with Arsenic Trioxide for Effective Suppression of KRAS-Mutant Cancers: A Promising Path at the Bedside

The turn-on mutations of the KRAS gene, coding a small GTPase coupling growth factor signaling, are contributing to nearly 25% of all human cancers, leading to highly malignant tumors with poor outcomes. Targeting of oncogenic KRAS remains a most challenging task in oncology. Recently, the specific...

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Detalles Bibliográficos
Autores principales: Burska, Agata N., Ilyassova, Bayansulu, Dildabek, Aruzhan, Khamijan, Medina, Begimbetova, Dinara, Molnár, Ferdinand, Sarbassov, Dos D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657932/
https://www.ncbi.nlm.nih.gov/pubmed/36359850
http://dx.doi.org/10.3390/cells11213454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9657932/
https://www.ncbi.nlm.nih.gov/pubmed/36359850
http://dx.doi.org/10.3390/cells11213454

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