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Extracellular Vesicles Isolated from Plasma of Multiple Myeloma Patients Treated with Daratumumab Express CD38, PD-L1, and the Complement Inhibitory Proteins CD55 and CD59
Daratumumab (DARA) has improved the outcome of treatment of multiple myeloma (MM). DARA acts via complement-dependent and -independent mechanisms. Resistance to DARA may result from upregulation of the complement inhibitory proteins CD55 and CD59, downregulation of the DARA target CD38 on myeloma ce...
Autores principales: | Brennan, Kieran, Iversen, Katrine F., Blanco-Fernández, Alfonso, Lund, Thomas, Plesner, Torben, Mc Gee, Margaret M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658084/ https://www.ncbi.nlm.nih.gov/pubmed/36359760 http://dx.doi.org/10.3390/cells11213365 |
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