UM-164, a Dual Inhibitor of c-Src and p38 MAPK, Suppresses Proliferation of Glioma by Reducing YAP Activity

SIMPLE SUMMARY: UM-164, as a high-potency c-Src inhibitor, is the original lead compound to be developed for targeting triple-negative breast cancer. Here we validated the fact that UM-164 induces the inhibition of glioma cell proliferation, migration and spheroid formation, as well as cell cycle ar...

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Detalles Bibliográficos
Autores principales: Xu, Huizhe, Zhang, Ye, Liu, Jia, Cui, Jing, Gan, Yu, Wu, Zhisheng, Chang, Youwei, Sui, Rui, Chen, Yi, Shi, Ji, Liang, Haiyang, Liu, Qiang, Sun, Shulan, Piao, Haozhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658092/
https://www.ncbi.nlm.nih.gov/pubmed/36358761
http://dx.doi.org/10.3390/cancers14215343

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