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Human Mesenchymal Stem Cell Secretome Driven T Cell Immunomodulation Is IL-10 Dependent

The Human Mesenchymal Stem Cell (hMSC) secretome has pleiotropic effects underpinning its therapeutic potential. hMSC serum-free conditioned media (SFCM) contains a variety of cytokines, with previous studies linking a changed secretome composition to physoxia. The Jurkat T cell model allowed the ef...

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Detalles Bibliográficos
Autores principales: Shephard, Matthew T., Merkhan, Marwan M., Forsyth, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658100/
https://www.ncbi.nlm.nih.gov/pubmed/36362383
http://dx.doi.org/10.3390/ijms232113596