Cargando…

Therapeutic Potential of Targeting the HMGB1/RAGE Axis in Inflammatory Diseases

High mobility group box 1 (HMGB1) is a nuclear protein that can interact with a receptor for advanced glycation end-products (RAGE; a multi-ligand immunoglobulin receptor) and mediates the inflammatory pathways that lead to various pathological conditions, such as cancer, diabetes, neurodegenerative...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Harbinder, Agrawal, Devendra K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658169/ https://www.ncbi.nlm.nih.gov/pubmed/36364135 http://dx.doi.org/10.3390/molecules27217311

Ejemplares similares

Therapeutic potential of targeting the receptor for advanced glycation end products (RAGE) by small molecule inhibitors
por: Singh, Harbinder, et al.
Publicado: (2022)

The Immune Tolerance Role of the HMGB1-RAGE Axis
por: Watanabe, Haruki, et al.
Publicado: (2021)

Impact of HMGB1, RAGE, and TLR4 in Alzheimer’s Disease (AD): From Risk Factors to Therapeutic Targeting
por: Paudel, Yam Nath, et al.
Publicado: (2020)

Molecular signaling of the HMGB1/RAGE axis contributes to cholesteatoma pathogenesis
por: Szczepanski, Miroslaw J., et al.
Publicado: (2014)

TREM-1, HMGB1 and RAGE in the Shoulder Tendon: Dual Mechanisms for Inflammation Based on the Coincidence of Glenohumeral Arthritis
por: Thankam, Finosh G., et al.
Publicado: (2016)

The HMGB1-RAGE axis modulates the growth of autophagy-deficient hepatic tumors
por: Khambu, Bilon, et al.
Publicado: (2020)

Circulating HMGB1 and RAGE as Clinical Biomarkers in Malignant and Autoimmune Diseases
por: Pilzweger, Christin, et al.
Publicado: (2015)

The HMGB1/RAGE Pro-Inflammatory Axis in the Human Placenta: Modulating Effect of Low Molecular Weight Heparin
por: Zenerino, Cristian, et al.
Publicado: (2017)

The role of HMGB1-RAGE axis in migration and invasion of hepatocellular carcinoma cell lines
por: Chen, Ruo-Chan, et al.
Publicado: (2014)

HMGB1-RAGE Axis Makes No Contribution to Cardiac Remodeling Induced by Pressure-Overload
por: Lin, Hairuo, et al.
Publicado: (2016)

Potential of the Angiotensin Receptor Blockers (ARBs) Telmisartan, Irbesartan, and Candesartan for Inhibiting the HMGB1/RAGE Axis in Prevention and Acute Treatment of Stroke
por: Kikuchi, Kiyoshi, et al.
Publicado: (2013)

Correction: HMGB1-RAGE Axis Makes No Contribution to Cardiac Remodeling Induced by Pressure-Overload
Publicado: (2016)

HMGB1/RAGE axis mediates the apoptosis, invasion, autophagy, and angiogenesis of the renal cell carcinoma
por: Wu, Cun-Zao, et al.
Publicado: (2018)

The SIRT1-HMGB1 axis: Therapeutic potential to ameliorate inflammatory responses and tumor occurrence
por: Wei, Lanyi, et al.
Publicado: (2022)

Therapeutic potential of HMGB1-targeting agents in sepsis
por: Wang, Haichao, et al.
Publicado: (2008)

Rosuvastatin reduces the pro-inflammatory effects of adriamycin on the expression of HMGB1 and RAGE in rats
por: Zhang, Haiyan, et al.
Publicado: (2018)

Mechanism of HMGB1–RAGE in Kawasaki disease with coronary artery injury
por: Qian, Biying, et al.
Publicado: (2020)

HMGB1/RAGE Axis Mediates the Apoptosis, Invasion, Autophay, and Angiogenesis of the Renal Cell Carcinoma [Corrigendum]
Publicado: (2022)

Targeting HMGB1: A Potential Therapeutic Strategy for Chronic Kidney Disease
por: Liu, Tongtong, et al.
Publicado: (2023)

HMGB1 and Toll-like receptors: potential therapeutic targets in autoimmune diseases
por: Ren, Wenxuan, et al.
Publicado: (2023)

Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury
por: Fan, Hong, et al.
Publicado: (2020)

Targeting the Crosstalk of Immune Response and Vascular Smooth Muscle Cells Phenotype Switch for Arteriovenous Fistula Maturation
por: Rai, Vikrant, et al.
Publicado: (2022)

Immunogenic Biomarkers HMGB1 and sRAGE Are Potential Diagnostic Tools for Ovarian Malignancies
por: Schröder, Lars, et al.
Publicado: (2023)

Ethyl pyruvate reduces organic dust-induced airway inflammation by targeting HMGB1-RAGE signaling
por: Bhat, Sanjana Mahadev, et al.
Publicado: (2019)

Inhibition of HMGB1/RAGE axis suppressed the lipopolysaccharide (LPS)-induced vicious transformation of cervical epithelial cells
por: You, Lifang, et al.
Publicado: (2021)

Oxidative stress and inflammatory markers in patients with COVID-19: Potential role of RAGE, HMGB1, GFAP and COX-2 in disease severity
por: Rocha Santos Passos, Fabiolla, et al.
Publicado: (2022)

sRAGE alleviates neutrophilic asthma by blocking HMGB1/RAGE signalling in airway dendritic cells
por: Zhang, Fang, et al.
Publicado: (2017)

The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone
por: Okui, Tatsuo, et al.
Publicado: (2020)

HMGB1 as a Potential Biomarker and Therapeutic Target for Malignant Mesothelioma
por: Wang, Yanbin, et al.
Publicado: (2019)

The S100B/RAGE Axis in Alzheimer's Disease
por: Leclerc, Estelle, et al.
Publicado: (2010)

HMGB1/RAGE axis mediates stress-induced RVLM neuroinflammation in mice via impairing mitophagy flux in microglia
por: Zhang, Shutian, et al.
Publicado: (2020)

RAGE and HMGB1 Expression in Orbital Tissue Microenvironment in Graves' Ophthalmopathy
por: Łacheta, Dominika, et al.
Publicado: (2021)

Receptor for Advanced Glycation Endproducts (RAGE), Its Ligands, and Soluble RAGE: Potential Biomarkers for Diagnosis and Therapeutic Targets for Human Renal Diseases
por: Lee, Eun Ji, et al.
Publicado: (2013)

Inhibition of HMGB1/RAGE-mediated endocytosis by HMGB1 antagonist box A, anti-HMGB1 antibodies, and cholinergic agonists suppresses inflammation
por: Yang, Huan, et al.
Publicado: (2019)

HMGB1/RAGE Signaling and Pro-Inflammatory Cytokine Responses in Non-HIV Adults with Active Pulmonary Tuberculosis
por: Lui, Grace, et al.
Publicado: (2016)

A Unique Anti-Cancer 3-Styrylchromone Suppresses Inflammatory Response via HMGB1-RAGE Signaling
por: Abe, Hideaki, et al.
Publicado: (2021)

TSLP and HMGB1: Inflammatory Targets and Potential Biomarkers for Precision Medicine in Asthma and COPD
por: Furci, Fabiana, et al.
Publicado: (2023)

The role of irreversible electroporation in promoting M1 macrophage polarization via regulating the HMGB1-RAGE-MAPK axis in pancreatic cancer
por: He, Chaobin, et al.
Publicado: (2021)

Extracellular HMGB1 interacts with RAGE and promotes chemoresistance in acute leukemia cells
por: Lai, Weixin, et al.
Publicado: (2021)

Soluble RAGE attenuates AngII-induced endothelial hyperpermeability by disrupting HMGB1-mediated crosstalk between AT1R and RAGE
por: Jeong, Jisu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_0vr4vh4kdflbuddctag0nkuvv0