Cargando…

Synthesis and Antioxidative Properties of 1,2,3,4-Tetrahydropyridine Derivatives with Different Substituents in 4-Position

Natural products are an excellent source of inspiration for the development of new drugs. Among them, betalains have been extensively studied for their antioxidant properties and potential application as natural food dyes. Herein, we describe the seven-step synthesis of new betalamic acid analogs wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aiello, Daniele, Jonas, Hendrik, Carbone, Anna, Carbone, Daniela, Pecoraro, Camilla, Tesoriere, Luisa, Köhler, Jens, Wünsch, Bernhard, Diana, Patrizia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658173/ https://www.ncbi.nlm.nih.gov/pubmed/36364252 http://dx.doi.org/10.3390/molecules27217423

Ejemplares similares

Photoinduced 1,2,3,4-tetrahydropyridine ring conversions
por: Turovska, Baiba, et al.
Publicado: (2015)

1,3,4-Oxadiazole and 1,3,4-Thiadiazole Nortopsentin Derivatives against Pancreatic Ductal Adenocarcinoma: Synthesis, Cytotoxic Activity, and Inhibition of CDK1
por: Carbone, Daniela, et al.
Publicado: (2023)

3-Ethyl 5-methyl 2-hydroxy-6-methyl-4-(4-nitrophenyl)-2-trifluoromethyl-1,2,3,4-tetrahydropyridine-3,5-dicarboxylate
por: Yu, Chen-Xia, et al.
Publicado: (2008)

Recent Developments in the Inhibition of Bacterial Adhesion as Promising Anti-Virulence Strategy
por: Pecoraro, Camilla, et al.
Publicado: (2023)

6-[(2-Chloropyridin-5-ylmethyl)(ethyl)azanyl]-4-(2-fluorophenyl)-1-methyl-5-nitro-1,2,3,4-tetrahydropyridin-2-one
por: Sun, Chuan-Wen, et al.
Publicado: (2012)

3-[4-(1H-Indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, Nortopsentin Analogues with Antiproliferative Activity
por: Parrino, Barbara, et al.
Publicado: (2015)

Practical and Efficient Synthesis of α-Aminophosphonic Acids Containing 1,2,3,4-Tetrahydroquinoline or 1,2,3,4-Tetrahydroisoquinoline Heterocycles
por: Ordóñez, Mario, et al.
Publicado: (2016)

Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation
por: Carbone, Anna, et al.
Publicado: (2020)

Substituent Effects on the Stability and Antioxidant Activity of Spirodiazaselenuranes
por: Lamani, Devappa S., et al.
Publicado: (2015)

3-(4-Chlorophenyldiazenyl)-1-methyl-1,4,5,6-tetrahydropyridine
por: Meneghetti, Fiorella, et al.
Publicado: (2008)

(S)-4-Phenyl-2-(1,2,3,4-tetrahydroisoquinolin-3-yl)-1,3-thiazole
por: Pawar, Sunayna, et al.
Publicado: (2011)

(S)-N-Benzyl-2-methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
por: Naicker, Tricia, et al.
Publicado: (2010)

(R)-4-Phenyl-2-[(S)-1,2,3,4-tetrahydroisoquinolin-3-yl]-4,5-dihydro-1,3-oxazole
por: Chakka, Sai K., et al.
Publicado: (2010)

Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs
por: Spanò, Virginia, et al.
Publicado: (2016)

New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity
por: Cascioferro, Stella, et al.
Publicado: (2019)

(S)-4-tert-Butyl-2-(1,2,3,4-tetrahydroisoquinolin-3-yl)-1,3-thiazole
por: Pawar, Sunayna, et al.
Publicado: (2012)

Nortopsentins as Leads from Marine Organisms for Anticancer and Anti-Inflammatory Agent Development
por: Pecoraro, Camilla, et al.
Publicado: (2023)

Mechanochemical Aza-Vinylogous Povarov Reactions for the Synthesis of Highly Functionalized 1,2,3,4-Tetrahydroquinolines and 1,2,3,4-Tetrahydro-1,5-Naphthyridines
por: Clerigué, José, et al.
Publicado: (2021)

4,4′-Bipyridine–butane-1,2,3,4-tetracarboxylic acid (1/1)
por: Najafpour, M. Mahdi, et al.
Publicado: (2008)

Butane-1,2,3,4-tetracarboxylic acid–4,4′-bipyridine (1/2)
por: Zhang, Ning, et al.
Publicado: (2009)

Discovery of the 3-Amino-1,2,4-triazine-Based Library as Selective PDK1 Inhibitors with Therapeutic Potential in Highly Aggressive Pancreatic Ductal Adenocarcinoma
por: Carbone, Daniela, et al.
Publicado: (2023)

Mécanique: terminales B Tn (F1.2.3.4.)
por: Lemasson, Claude, 1929-
Publicado: (1969)

1,2,3,4-Tetrahydroisoquinoline-2-sulfonamide
por: Bouasla, Radia, et al.
Publicado: (2008)

Butane-1,2,3,4-tetracarboxylic acid dihydrate
por: Cheng, Yu, et al.
Publicado: (2009)

Synthesis and Contractile Activity of Substituted 1,2,3,4-Tetrahydroisoquinolines
por: Ivanov, Iliyan, et al.
Publicado: (2011)

Synthesis and antioxidant evaluation of 4-(furan-2-yl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate esters
por: Mansouri, M., et al.
Publicado: (2012)

Cyclin Dependent Kinase-1 (CDK-1) Inhibition as a Novel Therapeutic Strategy against Pancreatic Ductal Adenocarcinoma (PDAC)
por: Wijnen, Rosa, et al.
Publicado: (2021)

(4R)-4-(Biphenyl-4-yl)-7-chloro-1,2,3,4-tetrahydroquinoline
por: Theissmann, Thomas, et al.
Publicado: (2011)

A Combination of Polymethoxyflavones from Citrus sinensis and Prenylflavonoids from Humulus lupulus Counteracts IL-1β-Induced Differentiated Caco-2 Cells Dysfunction via a Modulation of NF-κB/Nrf2 Activation
por: Restivo, Ignazio, et al.
Publicado: (2023)

e-Cadherin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson Disease
por: Cataldi, Samuela, et al.
Publicado: (2016)

Ethyl 4-(4-chlorophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
por: Nayak, Susanta K., et al.
Publicado: (2009)

Computational Study of Ortho-Substituent Effects on Antioxidant Activities of Phenolic Dendritic Antioxidants
por: Lee, Choon Young, et al.
Publicado: (2020)

(3S)-2-Benzyl-3-carboxy-1,2,3,4-tetrahydroisoquinolinium chloride monohydrate
por: Naicker, Tricia, et al.
Publicado: (2010)

Structural Manipulations of Marine Natural Products Inspire a New Library of 3-Amino-1,2,4-Triazine PDK Inhibitors Endowed with Antitumor Activity in Pancreatic Ductal Adenocarcinoma
por: Carbone, Daniela, et al.
Publicado: (2023)

1,2,3,4-Tetrahydrophenazine 5,10-dioxide
por: Sun, Tao, et al.
Publicado: (2010)

1,2,3,4-Tetramethylcyclopent-2-ene-1,4-diol
por: Blaurock, Steffen, et al.
Publicado: (2008)

1-(4-Chlorophenyl)-1H-1,2,3,4-tetrazole
por: Kim, Jong Tae, et al.
Publicado: (2012)

1-(4-Methylphenyl)-1H-1,2,3,4-tetrazole
por: Baek, Kwan, et al.
Publicado: (2012)

1,2,3,4-Tetrahydro-1,4-methanonaphthalene-2,3-diol
por: Xu, Jian, et al.
Publicado: (2008)

5-(4-Nitrobenzyl)-1H-1,2,3,4-tetrazole
por: Chen, Jin Mei, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_3057obbt0mie017a6q64fqlafb