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GABA(A) Receptor Modulators with a Pyrazolo[1,5-a]quinazoline Core: Synthesis, Molecular Modelling Studies and Electrophysiological Assays

As a continuation of our study in the GABA(A) receptor modulators field, we report the design and synthesis of new 8-chloropyrazolo[1,5-a]quinazoline derivatives. Molecular docking studies and the evaluation of the ‘Proximity Frequencies’ (exploiting our reported model) were performed on all the fin...

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Detalles Bibliográficos
Autores principales: Crocetti, Letizia, Guerrini, Gabriella, Melani, Fabrizio, Vergelli, Claudia, Mascia, Maria Paola, Giovannoni, Maria Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658275/
https://www.ncbi.nlm.nih.gov/pubmed/36361842
http://dx.doi.org/10.3390/ijms232113032

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