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Quetiapine Shortens the Lifespan of Caenorhabditis elegans through DOP-2, DAF-2 and RSKS-1

Recent studies implicate a key role of dopamine signaling in lifespan regulation. Our previous study found that quetiapine, an atypical antipsychotic drug that has antagonistic activity on dopamine D2-like receptors (D2Rs), shortened the lifespan of Caenorhabditis elegans (C. elegans). However, the...

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Detalles Bibliográficos
Autores principales:	Jiang, Yizhou, Gaur, Uma, Cao, Zhibai, Hou, Sheng-Tao, Zheng, Wenhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658709/ https://www.ncbi.nlm.nih.gov/pubmed/36361717 http://dx.doi.org/10.3390/ijms232112927

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