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Finite Element Modeling for Virtual Design to Miniaturize Medical Implants Manufactured of Nanostructured Titanium with Enhanced Mechanical Performance

The study is aimed to virtually miniaturize medical implants produced of the biocompatible Ti with improved mechanical performance. The results on the simulation-driven design of medical implants fabricated of nanostructured commercially pure Ti with significantly enhanced mechanical properties are...

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Autores principales: Kazarinov, Nikita, Stotskiy, Andrey, Polyakov, Alexander, Valiev, Ruslan Z., Enikeev, Nariman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658747/
https://www.ncbi.nlm.nih.gov/pubmed/36363009
http://dx.doi.org/10.3390/ma15217417
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author Kazarinov, Nikita
Stotskiy, Andrey
Polyakov, Alexander
Valiev, Ruslan Z.
Enikeev, Nariman
author_facet Kazarinov, Nikita
Stotskiy, Andrey
Polyakov, Alexander
Valiev, Ruslan Z.
Enikeev, Nariman
author_sort Kazarinov, Nikita
collection PubMed
description The study is aimed to virtually miniaturize medical implants produced of the biocompatible Ti with improved mechanical performance. The results on the simulation-driven design of medical implants fabricated of nanostructured commercially pure Ti with significantly enhanced mechanical properties are presented. The microstructure of initially coarse-grained Ti has been refined to ultrafine grain size by severe plastic deformation. The ultrafine-grained (UFG) Ti exhibits remarkably high static and cyclic strength, allowing to design new dental and surgical implants with miniaturized geometry. The possibilities to reduce the implant dimensions via virtual fatigue tests for the digital twins of two particular medical devices (a dental implant and a maxillofacial surgery plate) are explored with the help of finite element modeling. Additionally, the effect of variation in loading direction and the fixation methods for the tested implants are studied in order to investigate the sensitivity of the fatigue test results to the testing conditions. It is shown that the UFG materials are promising for the design of a new generation of medical products.
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spelling pubmed-96587472022-11-15 Finite Element Modeling for Virtual Design to Miniaturize Medical Implants Manufactured of Nanostructured Titanium with Enhanced Mechanical Performance Kazarinov, Nikita Stotskiy, Andrey Polyakov, Alexander Valiev, Ruslan Z. Enikeev, Nariman Materials (Basel) Article The study is aimed to virtually miniaturize medical implants produced of the biocompatible Ti with improved mechanical performance. The results on the simulation-driven design of medical implants fabricated of nanostructured commercially pure Ti with significantly enhanced mechanical properties are presented. The microstructure of initially coarse-grained Ti has been refined to ultrafine grain size by severe plastic deformation. The ultrafine-grained (UFG) Ti exhibits remarkably high static and cyclic strength, allowing to design new dental and surgical implants with miniaturized geometry. The possibilities to reduce the implant dimensions via virtual fatigue tests for the digital twins of two particular medical devices (a dental implant and a maxillofacial surgery plate) are explored with the help of finite element modeling. Additionally, the effect of variation in loading direction and the fixation methods for the tested implants are studied in order to investigate the sensitivity of the fatigue test results to the testing conditions. It is shown that the UFG materials are promising for the design of a new generation of medical products. MDPI 2022-10-22 /pmc/articles/PMC9658747/ /pubmed/36363009 http://dx.doi.org/10.3390/ma15217417 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kazarinov, Nikita
Stotskiy, Andrey
Polyakov, Alexander
Valiev, Ruslan Z.
Enikeev, Nariman
Finite Element Modeling for Virtual Design to Miniaturize Medical Implants Manufactured of Nanostructured Titanium with Enhanced Mechanical Performance
title Finite Element Modeling for Virtual Design to Miniaturize Medical Implants Manufactured of Nanostructured Titanium with Enhanced Mechanical Performance
title_full Finite Element Modeling for Virtual Design to Miniaturize Medical Implants Manufactured of Nanostructured Titanium with Enhanced Mechanical Performance
title_fullStr Finite Element Modeling for Virtual Design to Miniaturize Medical Implants Manufactured of Nanostructured Titanium with Enhanced Mechanical Performance
title_full_unstemmed Finite Element Modeling for Virtual Design to Miniaturize Medical Implants Manufactured of Nanostructured Titanium with Enhanced Mechanical Performance
title_short Finite Element Modeling for Virtual Design to Miniaturize Medical Implants Manufactured of Nanostructured Titanium with Enhanced Mechanical Performance
title_sort finite element modeling for virtual design to miniaturize medical implants manufactured of nanostructured titanium with enhanced mechanical performance
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658747/
https://www.ncbi.nlm.nih.gov/pubmed/36363009
http://dx.doi.org/10.3390/ma15217417
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