Cargando…
The Proteostasis Network: A Global Therapeutic Target for Neuroprotection after Spinal Cord Injury
Proteostasis (protein homeostasis) is critical for cellular as well as organismal survival. It is strictly regulated by multiple conserved pathways including the ubiquitin-proteasome system, autophagy, the heat shock response, the integrated stress response, and the unfolded protein response. These...
Autores principales: | Whittemore, Scott R., Saraswat Ohri, Sujata, Forston, Michael D., Wei, George Z., Hetman, Michal |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658791/ https://www.ncbi.nlm.nih.gov/pubmed/36359735 http://dx.doi.org/10.3390/cells11213339 |
Ejemplares similares
-
Inhibition of GADD34, the Stress-Inducible Regulatory Subunit of the Endoplasmic Reticulum Stress Response, Does Not Enhance Functional Recovery after Spinal Cord Injury
por: Saraswat Ohri, Sujata, et al.
Publicado: (2014) -
Improved locomotor recovery after contusive spinal cord injury in Bmal1(−/−) mice is associated with protection of the blood spinal cord barrier
por: Slomnicki, Lukasz P., et al.
Publicado: (2020) -
Antioxidant Protection of NADPH-Depleted Oligodendrocyte Precursor Cells Is Dependent on Supply of Reduced Glutathione
por: Kilanczyk, Ewa, et al.
Publicado: (2016) -
Opposite modulation of functional recovery following contusive spinal cord injury in mice with oligodendrocyte-selective deletions of Atf4 and Chop/Ddit3
por: Gao, Yonglin, et al.
Publicado: (2023) -
Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery
por: Wei, George Z., et al.
Publicado: (2021)