Design, Synthesis, and Mechanistic Study of 2-Pyridone-Bearing Phenylalanine Derivatives as Novel HIV Capsid Modulators

The AIDS pandemic is still of importance. HIV-1 and HIV-2 are the causative agents of this pandemic, and in the absence of a viable vaccine, drugs are continually required to provide quality of life for infected patients. The HIV capsid (CA) protein performs critical functions in the life cycle of H...

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Detalles Bibliográficos
Autores principales: Zhang, Xujie, Sun, Lin, Xu, Shujing, Shao, Xiaoyu, Li, Ziyi, Ding, Dang, Jiang, Xiangyi, Zhao, Shujie, Cocklin, Simon, Clercq, Erik De, Pannecouque, Christophe, Dick, Alexej, Liu, Xinyong, Zhan, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9658817/
https://www.ncbi.nlm.nih.gov/pubmed/36364467
http://dx.doi.org/10.3390/molecules27217640

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