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Long-Term Follow-Up after Testicular Torsion: Prospective Evaluation of Endocrine and Exocrine Testicular Function, Fertility, Oxidative Stress and Erectile Function

Background: This study investigates endocrine and exocrine testicular function, oxidative stress (OS) in semen, and erectile function in patients who underwent surgery for suspected testicular torsion (TT). Methods: We evaluated 49 patients over a mean follow-up of 101 months: n = 25 patients treate...

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Autores principales: Törzsök, Peter, Steiner, Christopher, Pallauf, Maximilian, Abenhardt, Michael, Milinovic, Ljiljana, Plank, Bethseba, Rückl, Alena, Sieberer, Manuela, Lusuardi, Lukas, Deininger, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659157/
https://www.ncbi.nlm.nih.gov/pubmed/36362741
http://dx.doi.org/10.3390/jcm11216507
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author Törzsök, Peter
Steiner, Christopher
Pallauf, Maximilian
Abenhardt, Michael
Milinovic, Ljiljana
Plank, Bethseba
Rückl, Alena
Sieberer, Manuela
Lusuardi, Lukas
Deininger, Susanne
author_facet Törzsök, Peter
Steiner, Christopher
Pallauf, Maximilian
Abenhardt, Michael
Milinovic, Ljiljana
Plank, Bethseba
Rückl, Alena
Sieberer, Manuela
Lusuardi, Lukas
Deininger, Susanne
author_sort Törzsök, Peter
collection PubMed
description Background: This study investigates endocrine and exocrine testicular function, oxidative stress (OS) in semen, and erectile function in patients who underwent surgery for suspected testicular torsion (TT). Methods: We evaluated 49 patients over a mean follow-up of 101 months: n = 25 patients treated with surgical exploration, n = 20 patients treated with detorsion, and n = 4 treated with orchiectomy. We performed semen analysis including Male infertility Oxidative System (MyOxSIS) analysis, physical examination, and evaluation of endocrine and erectile function. Results: OS, erectile function and spermiogram categories did not differ significantly between the groups. The interval from the onset of symptoms to surgery differed significantly between groups (p < 0.001). Preservation of the testes was associated with a higher round cell count (p = 0.002) and follicle stimulating hormone (FSH, p = 0.003). OS showed a significant positive correlation with the spermiogram category (0.337; p = 0.022). A negative correlation was observed between OS and age (p = 0.033), sperm concentration (p < 0.001) and total sperm count (p = 0.006). Conclusions: Endocrine, exocrine and erectile function are not significantly affected by TT in the long term. Orchiectomy results in elevated FSH and a lower round cell count compared to preservation of the testis.
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spelling pubmed-96591572022-11-15 Long-Term Follow-Up after Testicular Torsion: Prospective Evaluation of Endocrine and Exocrine Testicular Function, Fertility, Oxidative Stress and Erectile Function Törzsök, Peter Steiner, Christopher Pallauf, Maximilian Abenhardt, Michael Milinovic, Ljiljana Plank, Bethseba Rückl, Alena Sieberer, Manuela Lusuardi, Lukas Deininger, Susanne J Clin Med Article Background: This study investigates endocrine and exocrine testicular function, oxidative stress (OS) in semen, and erectile function in patients who underwent surgery for suspected testicular torsion (TT). Methods: We evaluated 49 patients over a mean follow-up of 101 months: n = 25 patients treated with surgical exploration, n = 20 patients treated with detorsion, and n = 4 treated with orchiectomy. We performed semen analysis including Male infertility Oxidative System (MyOxSIS) analysis, physical examination, and evaluation of endocrine and erectile function. Results: OS, erectile function and spermiogram categories did not differ significantly between the groups. The interval from the onset of symptoms to surgery differed significantly between groups (p < 0.001). Preservation of the testes was associated with a higher round cell count (p = 0.002) and follicle stimulating hormone (FSH, p = 0.003). OS showed a significant positive correlation with the spermiogram category (0.337; p = 0.022). A negative correlation was observed between OS and age (p = 0.033), sperm concentration (p < 0.001) and total sperm count (p = 0.006). Conclusions: Endocrine, exocrine and erectile function are not significantly affected by TT in the long term. Orchiectomy results in elevated FSH and a lower round cell count compared to preservation of the testis. MDPI 2022-11-02 /pmc/articles/PMC9659157/ /pubmed/36362741 http://dx.doi.org/10.3390/jcm11216507 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Törzsök, Peter
Steiner, Christopher
Pallauf, Maximilian
Abenhardt, Michael
Milinovic, Ljiljana
Plank, Bethseba
Rückl, Alena
Sieberer, Manuela
Lusuardi, Lukas
Deininger, Susanne
Long-Term Follow-Up after Testicular Torsion: Prospective Evaluation of Endocrine and Exocrine Testicular Function, Fertility, Oxidative Stress and Erectile Function
title Long-Term Follow-Up after Testicular Torsion: Prospective Evaluation of Endocrine and Exocrine Testicular Function, Fertility, Oxidative Stress and Erectile Function
title_full Long-Term Follow-Up after Testicular Torsion: Prospective Evaluation of Endocrine and Exocrine Testicular Function, Fertility, Oxidative Stress and Erectile Function
title_fullStr Long-Term Follow-Up after Testicular Torsion: Prospective Evaluation of Endocrine and Exocrine Testicular Function, Fertility, Oxidative Stress and Erectile Function
title_full_unstemmed Long-Term Follow-Up after Testicular Torsion: Prospective Evaluation of Endocrine and Exocrine Testicular Function, Fertility, Oxidative Stress and Erectile Function
title_short Long-Term Follow-Up after Testicular Torsion: Prospective Evaluation of Endocrine and Exocrine Testicular Function, Fertility, Oxidative Stress and Erectile Function
title_sort long-term follow-up after testicular torsion: prospective evaluation of endocrine and exocrine testicular function, fertility, oxidative stress and erectile function
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659157/
https://www.ncbi.nlm.nih.gov/pubmed/36362741
http://dx.doi.org/10.3390/jcm11216507
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