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A 3D–Predicted Structure of the Amine Oxidase Domain of Lysyl Oxidase–Like 2

Lysyl oxidase–like 2 (LOXL2) has been recognized as an attractive drug target for anti–fibrotic and anti–tumor therapies. However, the structure–based drug design of LOXL2 has been very challenging due to the lack of structural information of the catalytically–competent LOXL2. In this study; we gene...

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Detalles Bibliográficos
Autores principales: Meier, Alex A., Kuczera, Krzysztof, Mure, Minae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659206/
https://www.ncbi.nlm.nih.gov/pubmed/36362176
http://dx.doi.org/10.3390/ijms232113385