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The Biological Relevance of Papaverine in Cancer Cells

Papaverine (PPV), a benzylisoquinoline alkaloid, extracted from the Papaverine somniferum plant, is currently in clinical use as a vasodilator. Research has shown that PPV inhibits phosphodiesterase 10A (PDE10A,) resulting in the accumulation of cyclic adenosine 3′, 5′-monophosphate (cAMP) that affe...

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Detalles Bibliográficos
Autores principales: Gomes, Daniella Anthea, Joubert, Anna Margaretha, Visagie, Michelle Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659297/
https://www.ncbi.nlm.nih.gov/pubmed/36359780
http://dx.doi.org/10.3390/cells11213385