IER3IP1 is critical for maintaining glucose homeostasis through regulating the endoplasmic reticulum function and survival of β cells

Recessive mutations in IER3IP1 (immediate early response 3 interacting protein 1) cause a syndrome of microcephaly, epilepsy, and permanent neonatal diabetes (MEDS). IER3IP1 encodes an endoplasmic reticulum (ER) membrane protein, which is crucial for brain development; however, the role of IER3IP1 i...

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Detalles Bibliográficos
Autores principales: Yang, Jing, Zhen, Jinyang, Feng, Wenli, Fan, Zhenqian, Ding, Li, Yang, Xiaoyun, Huang, Yumeng, Shu, Hua, Xie, Jing, Li, Xin, Qiao, Jingting, Fan, Yuxin, Sun, Jinhong, Li, Na, Liu, Tengli, Wang, Shusen, Zhang, Xiaona, Arvan, Peter, Liu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659391/
https://www.ncbi.nlm.nih.gov/pubmed/36322741
http://dx.doi.org/10.1073/pnas.2204443119

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