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Lipopolysaccharide-induced Autophagy Increases SOX2-positive Astrocytes While Decreasing Neuronal Differentiation in the Adult Hippocampus

Inflammation alters the neural stem cell (NSC) lineage from neuronal to astrogliogenesis. However, the underlying mechanism is elusive. Autophagy contributes to the decline in adult hippocampal neurogenesis under E. coli lipopolysaccharide (LPS) stimulation. SRY-box transcription Factor 2 (SOX2) is...

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Detalles Bibliográficos
Autores principales: Liu, Wen-Chung, Wu, Chih-Wei, Fu, Mu-Hui, Tain, You-Lin, Liang, Chih-Kuang, Chen, I-Chun, Hung, Chun-Ying, Lee, Yu-Chi, Wu, Kay L.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659488/
https://www.ncbi.nlm.nih.gov/pubmed/36351841
http://dx.doi.org/10.5607/en22005

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