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A method to obtain purified free light chain monomers and dimers from urine samples of patients with multiple myeloma
Antibody light chains are synthesized in excess by plasma cells, and this excess can be secreted into biological fluids as dimers or monomers in various proportions. Structural differences between monomers or dimers of free light chains (FLC) can affect their biological functions and possibly their...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659499/ https://www.ncbi.nlm.nih.gov/pubmed/36103008 http://dx.doi.org/10.1007/s12026-022-09314-8 |