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Retrospective study of COVID-19 outcomes among healthcare workers in Rivers State, Nigeria

OBJECTIVE: To determine the illness severity and mortality among COVID-19-infected healthcare workers (HCWs). DESIGN: A retrospective cohort study using population-level data. Secondary analysis was conducted on collated data from the Public Health Emergency Operations Centre (PHEOC) at the State Mi...

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Autores principales: Eze-Emiri, Chidinma, Patrick, Foster, Igwe, Ezinne, Owhonda, Golden
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659712/
https://www.ncbi.nlm.nih.gov/pubmed/36368746
http://dx.doi.org/10.1136/bmjopen-2022-061826
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author Eze-Emiri, Chidinma
Patrick, Foster
Igwe, Ezinne
Owhonda, Golden
author_facet Eze-Emiri, Chidinma
Patrick, Foster
Igwe, Ezinne
Owhonda, Golden
author_sort Eze-Emiri, Chidinma
collection PubMed
description OBJECTIVE: To determine the illness severity and mortality among COVID-19-infected healthcare workers (HCWs). DESIGN: A retrospective cohort study using population-level data. Secondary analysis was conducted on collated data from the Public Health Emergency Operations Centre (PHEOC) at the State Ministry of Health, Rivers State, Nigeria. Data were gathered from the COVID-19 patient database of the PHEOC on demographics, place of work, illness severity and outcome. PARTICIPANTS: The cohort included all documented HCWs with confirmed COVID-19 infection (diagnosed by PCR). PRIMARY AND SECONDARY OUTCOME MEASURES: Illness severity defined as ‘hospitalisation required’ and treatment outcome labelled as ‘alive’ or ‘dead’ were the outcomes of interest. RESULTS: The mean age was 43 years and 50.5% of the cohort were female. Of the 301 HCWs infected, 187 patients were symptomatic with 32 requiring hospitalisation. Seven infected HCWs died of their COVID-19 infection, resulting in a case fatality ratio (CFR) of 2.3%. Population proportions for age groups, case presentation and mortality, would be significantly greater than those seen in the study population. Health professionals made up 79.7% (240) of the study cohort, with 68.8% (165) of them working at the teaching hospitals; the association between HCWs and health facilities they worked in, was significant. Symptomatic cases were more inclined to progress to severe illness ([Formula: see text] adjusted OR (aOR) 10.658, 95% CI 2.494 to 45.552); patients also had greater odds of dying from COVID-19 ([Formula: see text] aOR 1.079, 95% CI 1.02 to 1.141) per year increase in age adjusted for sex, case class and illness severity. CONCLUSIONS: Frontl-ine HCWs are at an increased risk of exposure to COVID-19 infections. In Nigeria, there is a higher risk of experiencing severe illness if symptomatic while infected with COVID-19. Preventive strategies, proper education and awareness must be put in place to protect HCWs. OBJECTIVE: To determine the illness severity and mortality among COVID-19-infected HCWs.
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spelling pubmed-96597122022-11-14 Retrospective study of COVID-19 outcomes among healthcare workers in Rivers State, Nigeria Eze-Emiri, Chidinma Patrick, Foster Igwe, Ezinne Owhonda, Golden BMJ Open Public Health OBJECTIVE: To determine the illness severity and mortality among COVID-19-infected healthcare workers (HCWs). DESIGN: A retrospective cohort study using population-level data. Secondary analysis was conducted on collated data from the Public Health Emergency Operations Centre (PHEOC) at the State Ministry of Health, Rivers State, Nigeria. Data were gathered from the COVID-19 patient database of the PHEOC on demographics, place of work, illness severity and outcome. PARTICIPANTS: The cohort included all documented HCWs with confirmed COVID-19 infection (diagnosed by PCR). PRIMARY AND SECONDARY OUTCOME MEASURES: Illness severity defined as ‘hospitalisation required’ and treatment outcome labelled as ‘alive’ or ‘dead’ were the outcomes of interest. RESULTS: The mean age was 43 years and 50.5% of the cohort were female. Of the 301 HCWs infected, 187 patients were symptomatic with 32 requiring hospitalisation. Seven infected HCWs died of their COVID-19 infection, resulting in a case fatality ratio (CFR) of 2.3%. Population proportions for age groups, case presentation and mortality, would be significantly greater than those seen in the study population. Health professionals made up 79.7% (240) of the study cohort, with 68.8% (165) of them working at the teaching hospitals; the association between HCWs and health facilities they worked in, was significant. Symptomatic cases were more inclined to progress to severe illness ([Formula: see text] adjusted OR (aOR) 10.658, 95% CI 2.494 to 45.552); patients also had greater odds of dying from COVID-19 ([Formula: see text] aOR 1.079, 95% CI 1.02 to 1.141) per year increase in age adjusted for sex, case class and illness severity. CONCLUSIONS: Frontl-ine HCWs are at an increased risk of exposure to COVID-19 infections. In Nigeria, there is a higher risk of experiencing severe illness if symptomatic while infected with COVID-19. Preventive strategies, proper education and awareness must be put in place to protect HCWs. OBJECTIVE: To determine the illness severity and mortality among COVID-19-infected HCWs. BMJ Publishing Group 2022-11-11 /pmc/articles/PMC9659712/ /pubmed/36368746 http://dx.doi.org/10.1136/bmjopen-2022-061826 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Public Health
Eze-Emiri, Chidinma
Patrick, Foster
Igwe, Ezinne
Owhonda, Golden
Retrospective study of COVID-19 outcomes among healthcare workers in Rivers State, Nigeria
title Retrospective study of COVID-19 outcomes among healthcare workers in Rivers State, Nigeria
title_full Retrospective study of COVID-19 outcomes among healthcare workers in Rivers State, Nigeria
title_fullStr Retrospective study of COVID-19 outcomes among healthcare workers in Rivers State, Nigeria
title_full_unstemmed Retrospective study of COVID-19 outcomes among healthcare workers in Rivers State, Nigeria
title_short Retrospective study of COVID-19 outcomes among healthcare workers in Rivers State, Nigeria
title_sort retrospective study of covid-19 outcomes among healthcare workers in rivers state, nigeria
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659712/
https://www.ncbi.nlm.nih.gov/pubmed/36368746
http://dx.doi.org/10.1136/bmjopen-2022-061826
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