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Thoracoscopic surgery for congenital diaphragmatic hernia in neonates: Should it be the first choice?

OBJECTIVE: Congenital diaphragmatic hernia (CDH) is an uncommon but potentially life-threatening surgical condition in neonates. Surgery can be performed by either open or thoracoscopic techniques. In this study, we compared the clinical efficacy, safety, and effectiveness of thoracoscopic and open...

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Autores principales: Liu, Rui, Zheng, Zebing, Tang, Chengyan, Zhang, Kaizhi, Du, Qing, Gong, Yuan, Zhu, Daiwei, Xia, Xingrong, Zhou, Wankang, Huang, Lu, Liu, Yuanmei, Jin, Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659751/
https://www.ncbi.nlm.nih.gov/pubmed/36389344
http://dx.doi.org/10.3389/fped.2022.1020062
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author Liu, Rui
Zheng, Zebing
Tang, Chengyan
Zhang, Kaizhi
Du, Qing
Gong, Yuan
Zhu, Daiwei
Xia, Xingrong
Zhou, Wankang
Huang, Lu
Liu, Yuanmei
Jin, Zhu
author_facet Liu, Rui
Zheng, Zebing
Tang, Chengyan
Zhang, Kaizhi
Du, Qing
Gong, Yuan
Zhu, Daiwei
Xia, Xingrong
Zhou, Wankang
Huang, Lu
Liu, Yuanmei
Jin, Zhu
author_sort Liu, Rui
collection PubMed
description OBJECTIVE: Congenital diaphragmatic hernia (CDH) is an uncommon but potentially life-threatening surgical condition in neonates. Surgery can be performed by either open or thoracoscopic techniques. In this study, we compared the clinical efficacy, safety, and effectiveness of thoracoscopic and open CDH repair. METHODS: A retrospective review of neonates with CDH who underwent operations at our hospital from 2013 to 2021 was performed. The various perioperative parameters were compared between neonates undergoing thoracoscopic and open surgery. RESULTS: There were 50 neonates in this study (37 in the thoracoscopic group and 13 in the open group). Thoracoscopic surgery was associated with significantly shorter hospital stay (13.32 vs. 18.77 days, p < 0.001); shorter duration of postoperative mechanical ventilation (3.70 vs. 5.98 days, p < 0.001); early feeding (4.34 vs. 7.46 days, p < 0.001); and shorter time to reach optimal feeding (8.21 vs. 13.38 days, p < 0.001). There was one postoperative death in the open group and no death in the thoracoscopic group. The median follow-up time of the two groups was 23.8 months (20.5 months in open group and 25.0 months in thoracoscopic group). Thoracoscopic surgery was associated with lower recurrence rates, but the difference was not statistically significant (2.7% vs. 7.7%, p = 0.456). CONCLUSION: Thoracoscopy CDH repair, a safe and effective surgical technique for neonates, has better cosmesis, faster postoperative recovery, and a lower recurrence rate than other procedures. It can be considered the first choice for CDH treatment for neonates among experienced surgeons.
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spelling pubmed-96597512022-11-15 Thoracoscopic surgery for congenital diaphragmatic hernia in neonates: Should it be the first choice? Liu, Rui Zheng, Zebing Tang, Chengyan Zhang, Kaizhi Du, Qing Gong, Yuan Zhu, Daiwei Xia, Xingrong Zhou, Wankang Huang, Lu Liu, Yuanmei Jin, Zhu Front Pediatr Pediatrics OBJECTIVE: Congenital diaphragmatic hernia (CDH) is an uncommon but potentially life-threatening surgical condition in neonates. Surgery can be performed by either open or thoracoscopic techniques. In this study, we compared the clinical efficacy, safety, and effectiveness of thoracoscopic and open CDH repair. METHODS: A retrospective review of neonates with CDH who underwent operations at our hospital from 2013 to 2021 was performed. The various perioperative parameters were compared between neonates undergoing thoracoscopic and open surgery. RESULTS: There were 50 neonates in this study (37 in the thoracoscopic group and 13 in the open group). Thoracoscopic surgery was associated with significantly shorter hospital stay (13.32 vs. 18.77 days, p < 0.001); shorter duration of postoperative mechanical ventilation (3.70 vs. 5.98 days, p < 0.001); early feeding (4.34 vs. 7.46 days, p < 0.001); and shorter time to reach optimal feeding (8.21 vs. 13.38 days, p < 0.001). There was one postoperative death in the open group and no death in the thoracoscopic group. The median follow-up time of the two groups was 23.8 months (20.5 months in open group and 25.0 months in thoracoscopic group). Thoracoscopic surgery was associated with lower recurrence rates, but the difference was not statistically significant (2.7% vs. 7.7%, p = 0.456). CONCLUSION: Thoracoscopy CDH repair, a safe and effective surgical technique for neonates, has better cosmesis, faster postoperative recovery, and a lower recurrence rate than other procedures. It can be considered the first choice for CDH treatment for neonates among experienced surgeons. Frontiers Media S.A. 2022-10-31 /pmc/articles/PMC9659751/ /pubmed/36389344 http://dx.doi.org/10.3389/fped.2022.1020062 Text en © 2022 Liu, Zheng, Tang, Zhang, Du, Gong, Zhu, Xia, Zhou, Huang, Liu and Jin. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Liu, Rui
Zheng, Zebing
Tang, Chengyan
Zhang, Kaizhi
Du, Qing
Gong, Yuan
Zhu, Daiwei
Xia, Xingrong
Zhou, Wankang
Huang, Lu
Liu, Yuanmei
Jin, Zhu
Thoracoscopic surgery for congenital diaphragmatic hernia in neonates: Should it be the first choice?
title Thoracoscopic surgery for congenital diaphragmatic hernia in neonates: Should it be the first choice?
title_full Thoracoscopic surgery for congenital diaphragmatic hernia in neonates: Should it be the first choice?
title_fullStr Thoracoscopic surgery for congenital diaphragmatic hernia in neonates: Should it be the first choice?
title_full_unstemmed Thoracoscopic surgery for congenital diaphragmatic hernia in neonates: Should it be the first choice?
title_short Thoracoscopic surgery for congenital diaphragmatic hernia in neonates: Should it be the first choice?
title_sort thoracoscopic surgery for congenital diaphragmatic hernia in neonates: should it be the first choice?
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659751/
https://www.ncbi.nlm.nih.gov/pubmed/36389344
http://dx.doi.org/10.3389/fped.2022.1020062
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