CD8 T Cells Target Antigen Cross-Presented by Bone Marrow Derived Cells to Induce Bystander Rejection of Grafts Lacking the Cognate Peptide-MHC

CD8 T cells play a key role in cancer immunotherapy and allograft rejection. However, it is not clear how they kill cells and tissues that do not have the agonist peptide-major histocompatibility complex (MHC) on their surface, as in the settings of MHC class I deficient tumors and indirect rejectio...

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Detalles Bibliográficos
Autores principales: Al-Adra, David P., Thangavelu, Govindarajan, Lin, Jiaxin, Chan, William F.N., Ellestad, Kristofor K., Boon, Louis, Anderson, Colin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659770/
https://www.ncbi.nlm.nih.gov/pubmed/36367048
http://dx.doi.org/10.1177/09636897221136149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659770/
https://www.ncbi.nlm.nih.gov/pubmed/36367048
http://dx.doi.org/10.1177/09636897221136149

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