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CD8 T Cells Target Antigen Cross-Presented by Bone Marrow Derived Cells to Induce Bystander Rejection of Grafts Lacking the Cognate Peptide-MHC
CD8 T cells play a key role in cancer immunotherapy and allograft rejection. However, it is not clear how they kill cells and tissues that do not have the agonist peptide-major histocompatibility complex (MHC) on their surface, as in the settings of MHC class I deficient tumors and indirect rejectio...
Autores principales: | Al-Adra, David P., Thangavelu, Govindarajan, Lin, Jiaxin, Chan, William F.N., Ellestad, Kristofor K., Boon, Louis, Anderson, Colin C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659770/ https://www.ncbi.nlm.nih.gov/pubmed/36367048 http://dx.doi.org/10.1177/09636897221136149 |
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