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GCAT: A network model of mutational influences between amino acid positions in PSD95(pdz3)
Proteins exist for more than 3 billion years: proof of a sustainable design. They have mechanisms coping with internal perturbations (e.g., amino acid mutations), which tie genetic backgrounds to diseases or drug therapy failure. One difficulty to grasp these mechanisms is the asymmetry of amino aci...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659846/ https://www.ncbi.nlm.nih.gov/pubmed/36387271 http://dx.doi.org/10.3389/fmolb.2022.1035248 |