Cargando…

Sex-specific transcriptional rewiring in the brain of Alzheimer’s disease patients

Sex-specific differences may contribute to Alzheimer’s disease (AD) development. AD is more prevalent in women worldwide, and female sex has been suggested as a disease risk factor. Nevertheless, the molecular mechanisms underlying sex-biased differences in AD remain poorly characterized. To this en...

Descripción completa

Detalles Bibliográficos
Autores principales:	Santiago, Jose A., Quinn, James P., Potashkin, Judith A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659968/ https://www.ncbi.nlm.nih.gov/pubmed/36389068 http://dx.doi.org/10.3389/fnagi.2022.1009368

Ejemplares similares

Physical Activity Rewires the Human Brain against Neurodegeneration
por: Santiago, Jose A., et al.
Publicado: (2022)

Physical activity and lifestyle modifications in the treatment of neurodegenerative diseases
por: Santiago, Jose A., et al.
Publicado: (2023)

The Impact of Disease Comorbidities in Alzheimer's Disease
por: Santiago, Jose A., et al.
Publicado: (2021)

Long-term social isolation stress exacerbates sex-specific neurodegeneration markers in a natural model of Alzheimer’s disease
por: Oliva, Carolina A., et al.
Publicado: (2023)

Transcriptomic and Network Analysis Highlight the Association of Diabetes at Different Stages of Alzheimer’s Disease
por: Santiago, Jose A., et al.
Publicado: (2019)

Network Analysis Identifies Sex-Specific Gene Expression Changes in Blood of Amyotrophic Lateral Sclerosis Patients
por: Santiago, Jose A., et al.
Publicado: (2021)

Sex differences in the structural rich-club connectivity in patients with Alzheimer’s disease
por: Kim, Soo-Jong, et al.
Publicado: (2023)

The role of sex differences in depression in pathologically defined Alzheimer’s disease
por: Tremblay, Cécilia, et al.
Publicado: (2023)

Sex-Specific Associations of Diabetes With Brain Structure and Function in a Geriatric Population
por: Thomas, Elias G., et al.
Publicado: (2022)

The role of ethnicity, biological sex, and psychotropic agents in early and late onset Alzheimer’s disease
por: Miller, Alyssa, et al.
Publicado: (2022)

APOE genotype and sex modulate Alzheimer’s disease pathology in aged EFAD transgenic mice
por: Balu, Deebika, et al.
Publicado: (2023)

Modulations of bioactive lipids and their receptors in postmortem Alzheimer’s disease brains
por: Kurano, Makoto, et al.
Publicado: (2022)

Imaging blood–brain barrier disruption in neuroinflammation and Alzheimer’s disease
por: Lee, Rae-Ling, et al.
Publicado: (2023)

Sex Differences in Brain and Cognition in de novo Parkinson's Disease
por: Oltra, Javier, et al.
Publicado: (2022)

Key Disease Mechanisms Linked to Amyotrophic Lateral Sclerosis in Spinal Cord Motor Neurons
por: Bottero, Virginie, et al.
Publicado: (2022)

An eXplainability Artificial Intelligence approach to brain connectivity in Alzheimer's disease
por: Amoroso, Nicola, et al.
Publicado: (2023)

Editorial: Imaging of the blood-brain barrier in Alzheimer's disease and related disorders
por: Uchida, Yuto, et al.
Publicado: (2023)

Specific White Matter Tracts and Diffusion Properties Predict Conversion From Mild Cognitive Impairment to Alzheimer’s Disease
por: Stone, David B., et al.
Publicado: (2021)

A Spatiotemporal Brain Network Analysis of Alzheimer’s Disease Based on Persistent Homology
por: Xing, Jiacheng, et al.
Publicado: (2022)

Feelings of loneliness and isolation: Social brain and social cognition in the elderly and Alzheimer's disease
por: Morese, Rosalba, et al.
Publicado: (2022)

An integrated neuroimaging-omics approach for the gut-brain communication pathways in Alzheimer’s disease
por: Sheng, Can, et al.
Publicado: (2023)

Dissociable Functional Brain Networks Associated With Apathy in Subcortical Ischemic Vascular Disease and Alzheimer’s Disease
por: Altunkaya, Sabri, et al.
Publicado: (2022)

Sex Differences in Large Artery Stiffness: Implications for Cerebrovascular Dysfunction and Alzheimer’s Disease
por: Kehmeier, Mackenzie N., et al.
Publicado: (2021)

Altered Interplay Among Large-Scale Brain Functional Networks Modulates Multi-Domain Anosognosia in Early Alzheimer’s Disease
por: Valera-Bermejo, Jose Manuel, et al.
Publicado: (2022)

Differential Patterns of Domain-Specific Cognitive Complaints and Awareness Across the Alzheimer’s Disease Spectrum
por: Cacciamani, Federica, et al.
Publicado: (2022)

Erratum: Feelings of loneliness and isolation: Social brain and social cognition in the elderly and Alzheimer's disease
Publicado: (2023)

Genetic background influences the 5XFAD Alzheimer's disease mouse model brain proteome
por: Hurst, Cheyenne D., et al.
Publicado: (2023)

The expression pattern of GDF15 in human brain changes during aging and in Alzheimer’s disease
por: Chiariello, Antonio, et al.
Publicado: (2023)

Blood-brain barrier dysfunction and Alzheimer’s disease: associations, pathogenic mechanisms, and therapeutic potential
por: Chen, Yanting, et al.
Publicado: (2023)

Aged Cattle Brain Displays Alzheimer's Disease-Like Pathology and Promotes Brain Amyloidosis in a Transgenic Animal Model
por: Moreno-Gonzalez, Ines, et al.
Publicado: (2022)

SCAD-Brain: a public database of single cell RNA-seq data in human and mouse brains with Alzheimer's disease
por: Li, Xin-Wen, et al.
Publicado: (2023)

Genome-Wide Association Study of Alzheimer’s Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer’s Disease Multimodal Biomarker Discovery Dataset
por: Homann, Jan, et al.
Publicado: (2022)

Intrinsic Brain Activity of Inferior Temporal Region Increased in Prodromal Alzheimer's Disease With Hearing Loss
por: Hong, Luwei, et al.
Publicado: (2022)

Contributions of blood–brain barrier imaging to neurovascular unit pathophysiology of Alzheimer’s disease and related dementias
por: Uchida, Yuto, et al.
Publicado: (2023)

Serum cortisol is negatively related to hippocampal volume, brain structure, and memory performance in healthy aging and Alzheimer’s disease
por: Dronse, Julian, et al.
Publicado: (2023)

Blood Transcriptomic Meta-analysis Identifies Dysregulation of Hemoglobin and Iron Metabolism in Parkinson’ Disease
por: Santiago, Jose A., et al.
Publicado: (2017)

Editorial: Systemic implications of Alzheimer's disease
por: Cortes, Constanza J., et al.
Publicado: (2023)

Endophenotypic effects of the SORL1 variant rs2298813 on regional brain volume in patients with late-onset Alzheimer’s disease
por: Chen, Chun-Yu, et al.
Publicado: (2022)

Preserved blood-brain barrier and neurovascular coupling in female 5xFAD model of Alzheimer’s disease
por: Zhukov, Oleg, et al.
Publicado: (2023)

Computational identification of key genes that may regulate gene expression reprogramming in Alzheimer’s patients
por: Potashkin, Judith A., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_tj3d2e74vbfg5d3r3hejsl60rp