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Glypican 1 promotes proliferation and migration in esophagogastric adenocarcinoma via activating AKT/GSK/β-catenin pathway

BACKGROUND: Glypican 1 (GPC1) is a heparan sulphate proteoglycan cell membrane protein. It is implicated in driving cancers of the breast, brain, pancreas, and prostate; however, its role in esophagogastric cancer (EGAC) remains unexplored. The aim of the study was to investigate and elucidate the m...

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Detalles Bibliográficos
Autores principales: Pratap, Akshay, Li, Anqi, Westbrook, Lindsey, Gergen, Anna K., Mitra, Sanchayita, Chauhan, Argudit, Cheng, Linling, Weyant, Michael J., McCarter, Martin, Wani, Sachin, Meguid, Robert Alexander, Mitchell, John D., Cohen, Mitchell, Fullerton, David, Meng, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660038/
https://www.ncbi.nlm.nih.gov/pubmed/36388647
http://dx.doi.org/10.21037/jgo-22-240