Cargando…

STING promotes proliferation and induces drug resistance in colorectal cancer by regulating the AMPK-mTOR pathway

BACKGROUND: In recent years, reports regarding stimulator of interferon genes (STING) and the progression of colorectal cancer (CRC) have emerged rapidly, yet their association remains controversial. This research was aimed to provide an insight into the prognostic biomarker and therapeutic target s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Huihui, Wang, Suo, Zhou, Xin, Sun, Jinbing, Zhou, Guoqiang, Zhou, Diyuan, Chen, Guoliang, Shi, Xinyu, Chen, Junjie, Shi, Bo, Tai, Qingliang, Mi, Xiuwei, Sun, Liang, Yao, Yizhou, He, Songbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660059/ https://www.ncbi.nlm.nih.gov/pubmed/36388670 http://dx.doi.org/10.21037/jgo-22-957

Ejemplares similares

Laparoscopic-Assisted Colorectal Resection Can Reduce the Inhibition of Immune Function Compared with Conventional Open Surgery: A Retrospective Clinical Study
por: Shi, Bo, et al.
Publicado: (2023)

The Association of Aberrant Expression of FGF1 and mTOR-S6K1 in Colorectal Cancer
por: Duan, Tinghui, et al.
Publicado: (2021)

Corrigendum: The Association of Aberrant Expression of FGF1 and mTOR-S6K1 in Colorectal Cancer
por: Duan, Tinghui, et al.
Publicado: (2021)

TBK1 Facilitates GLUT1-Dependent Glucose Consumption by suppressing mTORC1 Signaling in Colorectal Cancer Progression
por: Zhou, Diyuan, et al.
Publicado: (2022)

DAB2IP decreases cell growth and migration and increases sensitivity to chemotherapeutic drugs in colorectal cancer
por: Wu, Guanting, et al.
Publicado: (2021)

Pretreatment blood biomarkers combined with magnetic resonance imaging predict responses to neoadjuvant chemoradiotherapy in locally advanced rectal cancer
por: Shi, Xinyu, et al.
Publicado: (2022)

HKDC1 promotes the tumorigenesis and glycolysis in lung adenocarcinoma via regulating AMPK/mTOR signaling pathway
por: Wang, Xinyu, et al.
Publicado: (2020)

Dehydroepiandrosterone alleviates oleic acid-induced lipid metabolism disorders through activation of AMPK-mTOR signal pathway in primary chicken hepatocytes
por: Yao, Yao, et al.
Publicado: (2022)

Coordination of the AMPK, Akt, mTOR, and p53 Pathways under Glucose Starvation
por: Zhou, Yifan, et al.
Publicado: (2022)

Duck Tembusu virus induces incomplete autophagy via the ERK/mTOR and AMPK/mTOR signalling pathways to promote viral replication in neuronal cells
por: Wang, Qing, et al.
Publicado: (2023)

AMPK–mTOR Signaling and Cellular Adaptations in Hypoxia
por: Chun, Yoomi, et al.
Publicado: (2021)

YAP promotes the proliferation and migration of colorectal cancer cells through the Glut3/AMPK signaling pathway
por: Jiang, Linhua, et al.
Publicado: (2021)

Adrenomedullin alleviates the pyroptosis of Leydig cells by promoting autophagy via the ROS–AMPK–mTOR axis
por: Li, Ming-yong, et al.
Publicado: (2019)

Periplocin inhibits the growth of pancreatic cancer by inducing apoptosis via AMPK‐mTOR signaling
por: Xie, Gangyin, et al.
Publicado: (2020)

Metformin Potentiates the Effects of Anlotinib in NSCLC via AMPK/mTOR and ROS-Mediated Signaling Pathways
por: Zhu, Zhongling, et al.
Publicado: (2021)

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKα leading to apoptosis of neuronal cells
por: Chen, Long, et al.
Publicado: (2010)

Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway
por: Li, Liuran, et al.
Publicado: (2021)

Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-ULK1 signaling pathway
por: Yuan, Jie, et al.
Publicado: (2018)

Fatty acid 2-hydroxylation inhibits tumor growth and increases sensitivity to cisplatin in gastric cancer
por: Yao, Yizhou, et al.
Publicado: (2019)

Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway
por: Zhou, Feiya, et al.
Publicado: (2021)

Rhein Inhibits Autophagy in Rat Renal Tubular Cells by Regulation of AMPK/mTOR Signaling
por: Tu, Yue, et al.
Publicado: (2017)

Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway
por: Wu, Chenyu, et al.
Publicado: (2021)

AMPK–mTOR–Mediated Activation of Autophagy Promotes Formation of Dormant Polyploid Giant Cancer Cells
por: You, Bo, et al.
Publicado: (2022)

The protective roles of allicin on type 1 diabetes mellitus through AMPK/mTOR mediated autophagy pathway
por: Qian, Rengcheng, et al.
Publicado: (2023)

Trifolirhizin induces autophagy-dependent apoptosis in colon cancer via AMPK/mTOR signaling
por: Sun, Dongdong, et al.
Publicado: (2020)

Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells
por: Qu, Na, et al.
Publicado: (2022)

Vam6 reduces iNKT cell function in tumor via modulating AMPK/mTOR pathways
por: Bai, Shiyu, et al.
Publicado: (2023)

Glucose activates the primordial follicle through the AMPK/mTOR signaling pathway
por: Xu, Shengyu, et al.
Publicado: (2020)

Central Exercise Action Increases the AMPK and mTOR Response to Leptin
por: Ropelle, Eduardo R., et al.
Publicado: (2008)

TFEC contributes to cardiac hypertrophy by inhibiting AMPK/mTOR signaling
por: Zhao, Ting, et al.
Publicado: (2021)

AdipoR2 inhibits human glioblastoma cell growth through the AMPK/mTOR pathway
por: Jie, Chen, et al.
Publicado: (2021)

Irisin inhibits pancreatic cancer cell growth via the AMPK-mTOR pathway
por: Liu, Jiayu, et al.
Publicado: (2018)

lncRNA CASC19 Contributes to Radioresistance of Nasopharyngeal Carcinoma by Promoting Autophagy via AMPK-mTOR Pathway
por: Liu, Hongxia, et al.
Publicado: (2021)

DENV-2 NS1 promotes AMPK-LKB1 interaction to activate AMPK/ERK/mTOR signaling pathway to induce autophagy
por: Wu, Ning, et al.
Publicado: (2023)

UBE2O promotes hepatocellular carcinoma cell proliferation and invasion by regulating the AMPKα2/mTOR pathway
por: Shi, Zhan, et al.
Publicado: (2021)

Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway
por: Wang, Jiwei, et al.
Publicado: (2016)

Metformin Induces Autophagy via the AMPK-mTOR Signaling Pathway in Human Hepatocellular Carcinoma Cells
por: Gao, Chun, et al.
Publicado: (2020)

Phellodendrine promotes autophagy by regulating the AMPK/mTOR pathway and treats ulcerative colitis
por: Su, Shuai, et al.
Publicado: (2021)

Astrocyte-derived exosomal nicotinamide phosphoribosyltransferase (Nampt) ameliorates ischemic stroke injury by targeting AMPK/mTOR signaling to induce autophagy
por: Deng, Yang, et al.
Publicado: (2022)

CSC-3436 switched tamoxifen-induced autophagy to apoptosis through the inhibition of AMPK/mTOR pathway
por: Wu, Sheng-Tang, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_br15rspu9rjfkdf09hfud40ce7