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Regulation of survivin and caspase/Bcl-2/Cyto-C signaling by TDB-6 induces apoptosis of colorectal carcinoma LoVo cells

BACKGROUND: Colorectal carcinoma (CRC) treatment remains severe. Survivin is aberrantly overexpressed in CRC tissues and might be a potential target for CRC treatment. TDB-6 is a new taspine derivative. The purpose of this study is to investigate the inhibitory effect of TDB-6 on CRC and its underly...

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Detalles Bibliográficos
Autores principales:	Shi, Xianpeng, Wang, Pengchong, Zhu, Yaning, Li, Li, Yang, Tongfei, Sun, Jingying, He, Langchong, Zhou, Nan, Zhang, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660084/ https://www.ncbi.nlm.nih.gov/pubmed/36388656 http://dx.doi.org/10.21037/jgo-22-780

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