Multi-omic Characterization of Pancreatic Ductal Adenocarcinoma Relates CXCR4 mRNA Expression Levels to Potential Clinical Targets

PURPOSE: Chemokines are essential for immune cell trafficking and are considered to have a major impact on the composition of the tumor microenvironment. CX-chemokine receptor 4 (CXCR4) is associated with poor differentiation, metastasis, and prognosis in pancreatic ductal adenocarcinoma (PDAC). Thi...

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Detalles Bibliográficos
Autores principales: Kocher, Florian, Puccini, Alberto, Untergasser, Gerold, Martowicz, Agnieszka, Zimmer, Kai, Pircher, Andreas, Baca, Yasmine, Xiu, Joanne, Haybaeck, Johannes, Tymoszuk, Piotr, Goldberg, Richard M., Petrillo, Angelica, Shields, Anthony F., Salem, Mohamed E., Marshall, John L., Hall, Michael, Korn, W. Michael, Nabhan, Chadi, Battaglin, Francesca, Lenz, Heinz-Josef, Lou, Emil, Choo, Su-Pin, Toh, Chee-Keong, Gasteiger, Silvia, Pichler, Renate, Wolf, Dominik, Seeber, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9660543/
https://www.ncbi.nlm.nih.gov/pubmed/36112544
http://dx.doi.org/10.1158/1078-0432.CCR-22-0275

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