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Combined HPV 16 E2 and L1 methylation predict response to treatment with cidofovir and imiquimod in patients with vulval intraepithelial neoplasia

BACKGROUND: Topical cidofovir and imiquimod can effectively treat approximately 55% of patients with vulval intraepithelial neoplasia (VIN), thus avoiding the need for surgery. Human papillomavirus (HPV) [Formula: see text] gene methylation predicts response to treatment but a methylation measuremen...

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Detalles Bibliográficos
Autores principales: Hurt, Christopher Nicholas, Nedjai, Belinda, Alvarez-Mendoza, Carlos, Powell, Ned, Tristram, Amanda, Jones, Sadie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9661315/
https://www.ncbi.nlm.nih.gov/pubmed/35912731
http://dx.doi.org/10.3233/CBM-210448